2-Methylquinazoline-6-carboxylic acid CAS 648423-83-0
| CAS No. | 648423-83-0 |
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Methylquinazoline-6-carboxylic acid (CAS 648423-83-0), molecular formula C10H8N2O2 and molecular weight 188.18 g/mol, is a CATO reference standard with documented purity and traceability.
2-Methylquinazoline-6-carboxylic acid (C10H8N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-Methylquinazoline-6-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 2 |
Related Methylquinazoline Standards
- 2-Methylquinazoline-4-carboxylic acid (CAS 7671-97-8)
- 2-Methylquinazoline-4-carboxamide (CAS 7671-94-5)
- 1-methylquinazoline-2,4-dione (CAS 604-50-2)
- 6-Methylquinazoline-2,4(1H,3H)-dione (CAS 62484-16-6)
- 8-Methylquinazoline-2,4(1H,3H)-dione (CAS 67449-23-4)
- 2-Methylquinazoline-4-thiol (CAS 6484-28-2)
- 4-Methylquinazoline-2-thiol (CAS 25809-91-0)
- 3-Methylquinazoline-2,4(1h,3h)-dione (CAS 607-19-2)
Recommended Standards
- 2-Nitro-1-naphthalenamine (CAS 607-23-8)
- 2-Methylindazole-3,6-dicarbaldehyde (CAS 2092000-88-7)
- 2-Oxo-1,2-dihydroquinoline-3-carbaldehyde oxime (CAS 56682-66-7)
- 2-Methyl-8-nitroquinoline (CAS 881-07-2)
- (S)-1-Hydroxy-2,3-dihydro-1H-indene-4-carbonitrile (CAS 125225-26-5)
- 1-(1-Ethyl-1H-1,2,3-triazol-4-yl)ethanone (CAS 134926-94-6)
- 4-(5-Methyl-4-phenyl-1H-1,2,3-triazol-1-yl)aniline (CAS 84292-44-4)
- 2-(4-(Difluoromethyl)-6-iodo-2-methylpyridin-3-yl)acetonitrile (CAS 1807093-91-9)
- 6-(P-tolyloxy)nicotinaldehyde (CAS 338960-65-9)
- 4-Oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-2-carboxylic acid (CAS 2091705-21-2)
- Methyl 2-amino-2-(4-chloro-3-fluorophenyl)acetate hydrochloride (CAS 1395078-35-9)
- 4-(((5-Bromothiophen-2-yl)methylene)amino)-3-(3-ethoxyphenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 613249-88-0)
- 4-(1H-imidazol-2-yl)phthalazin-1(2H)-one (CAS 57594-20-4)
- Antiarrhythmic peptide (cattle atrium) (CAS 81771-37-1)
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