methyl 3-[(4-chlorobenzyl)amino]-2-(2-fluoroacetyl)acrylate CAS 648427-35-4
| CAS No. | 648427-35-4 |
| Molecular Formula | C13H13ClFNO3 |
| Molecular Weight | 285.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies methyl 3-[(4-chlorobenzyl)amino]-2-(2-fluoroacetyl)acrylate (CAS 648427-35-4), a certified reference material (molecular formula C13H13ClFNO3, MW 285.70 g/mol) for analytical method development and quality control.
Structurally, methyl 3-[(4-chlorobenzyl)amino]-2-(2-fluoroacetyl)acrylate (C13H13ClFNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 285.70 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H13ClFNO3 |
| Molecular Weight | 285.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related methyl Standards
- N-(3-Chlorobenzyl)-3-(trifluoromethyl)aniline (CAS 1024319-00-3)
- 1-(2-Chlorobenzyl)-1H-indole-2-carboxylic acid (CAS 943109-68-0)
- 1-(2-Chlorobenzyl)-1H-indole-3-carboxylic acid (CAS 93548-85-7)
- 1-(2-Chlorobenzyl)-4-hydroxyquinolin-2(1H)-one (CAS 696656-56-1)
- 1-(4-Chlorobenzyl)-1H-indole-2-carboxylic acid (CAS 220677-67-8)
- 1-(4-Chlorobenzyl)-5-methylindoline-2,3-dione (CAS 303998-01-8)
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- 6-(2-Chlorobenzyl)-5-oxothiomorpholine-3-carboxylic acid (CAS 1269527-41-4)
Recommended Standards
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- Semaglutide Impurity 122 (CAS CATO-C4X-2226122)
Why CATO?
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