4-(Diethylamino)quinazoline-6-carbaldehyde CAS 648449-16-5
| CAS No. | 648449-16-5 |
| Molecular Formula | C13H15N3O |
| Molecular Weight | 229.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(Diethylamino)quinazoline-6-carbaldehyde (C13H15N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
4-(Diethylamino)quinazoline-6-carbaldehyde (CAS 648449-16-5), molecular formula C13H15N3O and molecular weight 229.28 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H15N3O |
| Molecular Weight | 229.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 4-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)phenol (CAS 923235-74-9)
- 4-(Piperazin-1-yl)-6-(1H-pyrrol-1-yl)pyrimidine (CAS 2095409-39-3)
- 4-(5-Phenyl-1,2,4-oxadiazol-3-yl)piperidine (CAS 716313-84-7)
- 4-Amino-5-cyclopropyl-1-methyl-2-phenyl-2,3-dihydro-1h-pyrazol-3-one (CAS 856847-31-9)
- 2,6-Dichloropyridine-4-sulfonyl chloride (CAS 1058741-91-5)
- 3-((Tetrahydro-2H-pyran-4-yl)oxy)propanoic acid (CAS 193340-03-3)
- 2-Bromo-1-(difluoromethyl)-3-nitrobenzene (CAS 1261819-77-5)
- Eltrombopag Impurity 94 (CAS 1176777-76-6)
- Dimethyl 1-(4-fluorophenyl)-1H-pyrazole-3,4-dicarboxylate (CAS 358723-11-2)
- Theobromine-d6 (CAS 117490-40-1)
- 4-(4-(3,4-Dimethoxybenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)-1-methyl-1H-pyrazol-5-amine (CAS 956371-02-1)
- 4-(4-(Dimethylamino)phenyl)-5-hydroxyisoquinolin-1(2H)-one (CAS 656234-42-3)
- 1-Chloro-4-iodo-5-nitro-2-(trifluoromethyl)benzene (CAS 2383042-48-4)
- [γ-Glu]15 Semaglutide (CAS CATO-C4X-222690)
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