(E)-3-[5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-1-(4-chlorophenyl)-2-propen-1-one CAS 648859-48-7
| CAS No. | 648859-48-7 |
| Molecular Formula | C14H9Cl2F3N2O |
| Molecular Weight | 349.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (E)-3-[5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-1-(4-chlorophenyl)-2-propen-1-one (CAS 648859-48-7), a certified reference material (molecular formula C14H9Cl2F3N2O, MW 349.14 g/mol) for analytical method development and quality control.
The molecular framework of (E)-3-[5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-1-(4-chlorophenyl)-2-propen-1-one (C14H9Cl2F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-3-[5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-1-(4-chlorophenyl)-2-propen-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9Cl2F3N2O |
| Molecular Weight | 349.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- 4-Chloro-N-(6-chloro-4-(trifluoromethyl)-pyridin-2-yl)-N-methylbenzamide (CAS 1311279-81-8)
- (E)-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}[1-(4-chlorophenyl)ethylidene]amine (CAS 338978-33-9)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(4-chlorophenyl)acetamide (CAS 213993-82-9)
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(3-chlorophenyl)acetamide (CAS 338407-76-4)
- 2-Chloro-n-{3-[n'-(2-chloroacetyl)hydrazinecarbonyl]-5-nitrophenyl}acetamide (CAS 851169-32-9)
- Methyl 5-chloro-1-(4-chlorophenyl)-4-oxo-1,4-dihydrocinnoline-3-carboxylate (CAS 146743-26-2)
- 4-Chloro-5-((3-chlorophenoxy)methyl)-1-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (CAS 1024297-59-3)
- Ethyl 2-(6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetate (CAS 193979-48-5)
Recommended Standards
- (S)-2-(Dimethylamino)-3-hydroxypropanoic acid (CAS 2812-34-2)
- Ethyl 3-iodo-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-2-carboxylate (CAS 1956318-08-3)
- 1-(((5-(4-Bromophenyl)oxazol-2-yl)methylene)amino)imidazolidine-2,4-dione (CAS 64748-79-4)
- 6,7-Dichloro-2-(2-nitrophenyl)quinoline-5,8-dione (CAS 61472-28-4)
- 2-(3-Hydroxyphenyl)-2-(methylamino)acetonitrile (CAS 1040056-60-7)
- Procion Red MX 8B (CAS 57583-69-4)
- (6-Cyclopropylpyridin-2-yl)methanamine hydrochloride (CAS 2490709-55-0)
- methyl 5-(1-hydroxyethyl)furan-3-carboxylate (CAS 1803605-59-5)
- (3,4-Bis(difluoromethoxy)phenyl)methanol (CAS 153587-06-5)
- Methyl 4-bromo-1-methyl-1H-indole-6-carboxylate (CAS 1246867-53-7)
- (2E)-2-[(E)-3-(4-Chloro-2-methylphenoxy)benzoyl]-3-(dimethylamino)prop-2-enenitrile (CAS 1164517-44-5)
- (S)-1-(2-bromo-4-fluorophenyl)ethan-1-amine (CAS 1228569-18-3)
- 4-(4-Fluorophenyl)-2-methoxypyridine-3-carbonitrile (CAS 478245-82-8)
- Peptide YY (13-36) (canine, mouse, porcine, rat) (CAS 86895-09-2)
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