5-Chloro-7-(o-tolyl)quinolin-8-ol CAS 648896-39-3
| CAS No. | 648896-39-3 |
| Molecular Formula | C16H12ClNO |
| Molecular Weight | 269.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 5-Chloro-7-(o-tolyl)quinolin-8-ol is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 269.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
5-Chloro-7-(o-tolyl)quinolin-8-ol (CAS 648896-39-3), molecular formula C16H12ClNO and molecular weight 269.73 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12ClNO |
| Molecular Weight | 269.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-benzyl-3-chloro-5-phenyl-4H-1,2,4-triazole (CAS 1020043-28-0)
- 6-Chloro-8-methyl-3-phenylquinolin-2-ol (CAS 1031928-31-0)
- 5-Chloro-8-methyl-2-phenylquinolin-4-ol (CAS 1070879-82-1)
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Recommended Standards
- 5-Chloro-7-(m-tolyl)quinolin-8-ol (CAS 648896-43-9)
- 6-(Benzyloxy)-2-chloroquinoline (CAS 623144-17-2)
- 5-Chloro-2-(naphthalen-2-yloxy)aniline (CAS 32219-17-3)
- 6-(Benzyloxy)-4-chloroquinoline (CAS 863786-01-0)
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