7-(Benzo[b]thiophen-2-yl)-5-chloroquinolin-8-ol CAS 648896-46-2
| CAS No. | 648896-46-2 |
| Molecular Formula | C17H10ClNOS |
| Molecular Weight | 311.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, 7-(Benzo[b]thiophen-2-yl)-5-chloroquinolin-8-ol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 311.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 7-(Benzo[b]thiophen-2-yl)-5-chloroquinolin-8-ol (CAS 648896-46-2), a certified reference material (molecular formula C17H10ClNOS, MW 311.79 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H10ClNOS |
| Molecular Weight | 311.79 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- Ceritinib Impurity 82 (CAS CATO-C4X-104882)
- 4-(2-Isopropoxyphenyl)-1H-pyrrole-3-carbonitrile (CAS 87388-22-5)
- 2-[2-(5-bromo-1h-indol-1-yl)acetamido]acetic acid (CAS 1144446-66-1)
- N-(hydrazinecarbonothioyl)pivalamide (CAS 914347-05-0)
- 1-(4-Fluorophenyl)-N-methylcyclopropane-1-carboxamide (CAS 1210889-55-6)
- 2-[(3-Chlorophenyl)amino]propanohydrazide (CAS 1397005-54-7)
- 2-Ethyl-6-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 63736-04-9)
- BGT1-IN-9 (CAS 185444-92-2)
- methyl 4-fluoropiperidine-4-carboxylate;hydrochloride (CAS 1400797-26-3)
- Ethyl 4-methyl-5-oxopyrrolidine-3-carboxylate (CAS 61334-14-3)
- Tau Peptide (301-315) trifluoroacetate salt (CAS 330456-48-9)
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