2-Chloro-5-(5-methyl-1H-1,2,4-triazol-3-yl)aniline CAS 648917-60-6
| CAS No. | 648917-60-6 |
| Molecular Formula | C9H9ClN4 |
| Molecular Weight | 208.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-5-(5-methyl-1H-1,2,4-triazol-3-yl)aniline.
2-Chloro-5-(5-methyl-1H-1,2,4-triazol-3-yl)aniline (CAS 648917-60-6), molecular formula C9H9ClN4 and molecular weight 208.65 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-5-(5-methyl-1H-1,2,4-triazol-3-yl)aniline (C9H9ClN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-5-(5-methyl-1H-1,2,4-triazol-3-yl)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9ClN4 |
| Molecular Weight | 208.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 6-Chloro-3-cyclobutyl-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1094292-72-4)
- 6-Chloro-3-(2-methylcyclopropyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1094292-73-5)
- 2-Chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrazine (CAS 1133082-92-4)
- 5-Chloro-6-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-3-amine (CAS 1135283-22-5)
- 2-Chloro-5-methyl-4-(1-methyl-1H-pyrazol-5-yl)pyrimidine (CAS 1202986-04-6)
- 3-Chloro-6-methyl-4-(1-methyl-1h-imidazol-2-yl)pyridazine (CAS 1209062-25-8)
- 3-Chloro-6-(4,5-dimethyl-1H-imidazol-1-yl)pyridazine (CAS 1248926-89-7)
- 4-Chloro-3-(1-methyl-1h-1,2,4-triazol-5-yl)aniline (CAS 1249590-54-2)
Recommended Standards
- 2-Chloro-4-(3,5-dimethyl-1h-pyrazol-1-yl)pyrimidine (CAS 52476-66-1)
- 3-Chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine (CAS 29334-67-6)
- 2-((1H-1,2,3-Triazol-1-yl)methyl)-5-chloroaniline (CAS 922711-45-3)
- 4-(2-(Chloromethyl)hydrazono)-1,4-dihydroquinazoline (CAS 61164-83-8)
- 6-Chloro-8-iodo-[1,2,4]triazolo[1,5-a]pyridine (CAS 1415314-22-5)
- 4-Ethyl-5-methylisoxazol-3-amine (CAS 177266-03-4)
- (4'-Hydroxy-[1,1'-biphenyl]-2-yl)(pyrrolidin-3-yl)methanone (CAS 1261947-62-9)
- 2-Chloro-n-[(3-chlorophenyl)methyl]-n-methylacetamide (CAS 39086-64-1)
- Drotaverin Impurity 43 (CAS CATO-C4X-243543)
- 4-Trifluoromethanesulfonylbenzene-1,2-diamine (CAS 2355-16-0)
- tert-Butyl (R)-2-(((tert-butyldiphenylsilyl)oxy)methyl)-5-oxopyrrolidine-1-carboxylate (CAS 138629-30-8)
- Methyl 2,4-difluoro-5-methylbenzoate (CAS 1162674-66-9)
- 2-(3-Chlorophenyl)-2-morpholinoethylamine (CAS 866781-99-9)
- Neuropeptide Y (free acid) (human, rat) trifluoroacetate salt (CAS 99575-89-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com