Ethyl 4,4,4-trifluoro-3-hydroxy-3-methylbutanoate CAS 649-67-2
| CAS No. | 649-67-2 |
| Molecular Formula | C7H11F3O3 |
| Molecular Weight | 200.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 4,4,4-trifluoro-3-hydroxy-3-methylbutanoate.
CATO supplies Ethyl 4,4,4-trifluoro-3-hydroxy-3-methylbutanoate (CAS 649-67-2), a certified reference material (molecular formula C7H11F3O3, MW 200.16 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, Ethyl 4,4,4-trifluoro-3-hydroxy-3-methylbutanoate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 200.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H11F3O3 |
| Molecular Weight | 200.16 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Ethyl Standards
- 4,4,4-Trifluoro-1-phenylbut-2-yn-1-ol (CAS 128746-89-4)
- Butyl 3,3,3-trifluoro-2-hydroxypropanoate (CAS 149526-96-5)
- 1,1,1-Trifluoro-2-phenylbut-3-yn-2-ol (CAS 99727-20-5)
- 1,1,1-Trifluoro-4-phenylbut-3-en-2-one (CAS 3108-32-5)
- 1,1,1-Trifluoro-4-phenylbut-3-en-2-one (CAS 86571-25-7)
- 2,2,2-Trifluoro-N-[2-[(2-hydroxyethyl)amino]ethyl]-acetamide (CAS 364056-54-2)
- 4,4,4-Trifluoro-1-phenylbut-2-en-1-one (CAS 3108-34-7)
- Ethyl 4,4,4-trifluoro-3-hydroxy-2-methylbutanoate (CAS 91600-33-8)
Recommended Standards
- Ethyl 5,5,5-trifluoro-4-hydroxypentanoate (CAS 70961-06-7)
- Ethyl 2-fluoro-3-(furan-2-yl)-3-oxopropanoate (CAS 357286-30-7)
- Methyl 3-fluoro-4-hydroxy-2-methoxybenzoate (CAS 2091676-09-2)
- Enzalutamide Impurity 36 (CAS 208122-06-9)
- 5-(tert-Butyl)-4-((4-hydroxy-6-(4-hydroxyphenethyl)-6-isopropyl-2-oxo-5,6-dihydro-2H-pyran-3-yl)thio)-2-methylphenyl 4-cyanobenzenesulfonate (CAS 263842-84-8)
- 2,6-Diamino-5-(5-hydroxypentyl)pyrimidin-4(1H)-one (CAS 647831-41-2)
- 4-Allyl-5-(2-(3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazol-4-yl)-4H-1,2,4-triazole-3-thiol (CAS 956964-73-1)
- 1-(1-Butyl-5-chloro-1H-benzo[d]imidazol-2-yl)ethan-1-amine (CAS 1312137-92-0)
- N-(1-((4-Fluorophenyl)sulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)methanesulfonamide (CAS 951519-55-4)
- N-Ethyl-4-bromobenzylamine (CAS 856795-95-4)
- Methyl 4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate (CAS 958332-63-3)
- 5-(5-Bromoisoindolin-1-yl)oxazole (CAS 1422344-23-7)
- (S)-Methyl 2-amino-2-(4-bromophenyl)acetate hydrochloride (CAS 1391528-74-7)
- Tirzepatide Impurity 38 (CAS CATO-C4X-324038)
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