3-(5-(4-Chloro-2-nitrophenyl)furan-2-yl)acrylic acid CAS 649573-07-9
| CAS No. | 649573-07-9 |
| Molecular Formula | C13H8ClNO5 |
| Molecular Weight | 293.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-(5-(4-Chloro-2-nitrophenyl)furan-2-yl)acrylic acid (CAS 649573-07-9) is a high-purity analytical reference standard with the molecular formula C13H8ClNO5 and a molecular weight of 293.66 g/mol.
The molecular framework of 3-(5-(4-Chloro-2-nitrophenyl)furan-2-yl)acrylic acid (C13H8ClNO5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H8ClNO5 |
| Molecular Weight | 293.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
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- 4-Chlorophenyl 5-nitropyridin-2-ylcarbamate (CAS 1984037-71-9)
- 4-Nitrophenyl (5-chloropyridin-2-yl)carbamate (CAS 536746-34-6)
- 1-(2,6-Dimethylpiperazin-1-yl)ethan-1-one hydrochloride (CAS 1955554-68-3)
- n-Benzyl-1-chloro-n-ethylmethanesulfonamide (CAS 1339753-90-0)
- 3-(2-(Pyrrolidin-1-yl)ethyl)aniline dihydrochloride (CAS 1427380-35-5)
- [2-(3-Methyl-[1,2,4]oxadiazol-5-yl)-phenoxy]-acetic acid (CAS 878618-12-3)
- 5-bromo-4-fluoro-1H-pyridin-2-one (CAS 1805590-93-5)
- 2-(Benzo[d][1,3]dioxol-5-yl)-N-(4-(dimethylamino)phenyl)-3-(4-methoxyphenyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide (CAS 1022413-55-3)
- 1-(Piperidin-1-yl)propane-1-thione (CAS 5309-95-5)
- 3-(Chlorosulfonyl)-2,4,5-trifluorobenzoic acid (CAS 1242340-07-3)
- 2-Deoxyuridine-5,5-d (CAS 478511-30-7)
- Tirzepatide Impurity 22 X TFA Salt (CAS CATO-C4X-324022)
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