4-Hydroxyisoxazole-3,5-dicarboxylic acid CAS 6496-98-6
| CAS No. | 6496-98-6 |
| Molecular Formula | C5H3NO6 |
| Molecular Weight | 173.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Hydroxyisoxazole-3,5-dicarboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-Hydroxyisoxazole-3,5-dicarboxylic acid (CAS 6496-98-6), molecular formula C5H3NO6 and molecular weight 173.08 g/mol, is a CATO reference standard with documented purity and traceability.
4-Hydroxyisoxazole-3,5-dicarboxylic acid (C5H3NO6) contains a carbohydrate-derived structure, an amide group. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H3NO6 |
| Molecular Weight | 173.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Hydroxyisoxazole Standards
- Ethyl 3-hydroxyisoxazole-5-carboxylate (CAS 13626-61-4)
- Ethyl 4-hydroxyisoxazole-3-carboxylate (CAS 84691-16-7)
- Methyl 3-Hydroxyisoxazole-5-carboxylate (CAS 10068-07-2)
- Methyl 5-hydroxyisoxazole-3-carboxylate (CAS 1557026-77-3)
- 3-Hydroxyisoxazole-5-carboxylic acid (CAS 13626-60-3)
- 4-Hydroxyisoxazole-3-carboxylic Acid (CAS 178316-77-3)
- 5-Hydroxyisoxazole-3-carboxylic acid (CAS 933726-73-9)
- 3-Hydroxyisoxazole-5-carboxamide (CAS 14016-01-4)
Recommended Standards
- 3-Carbamoyl-4-carboxy-1,2,5-oxadiazole 2-oxide (CAS 204335-82-0)
- 5-Nitrobarbituric Acid (CAS 480-68-2)
- 2-(4-Nitro-1,2,5-oxadiazol-3-yl)acetic acid (CAS 186044-14-4)
- 5-Nitropyrimidine-2,4,6(1H,3H,5H)-trione x hydrate (CAS 209529-81-7)
- 3-Amino-4-(benzylamino)benzamide (CAS 66315-41-1)
- Azetidin-3-yl(4-(trifluoromethyl)phenyl)methanone hydrochloride (CAS 1864074-82-7)
- 4-Bromo-3,6-dichloro-1H-indazole (CAS 887568-33-4)
- Platinum,bis[2-[(2,3-η)-2-propenyl]phenolato-O]- (CAS 42718-74-1)
- 1-(Aminomethyl)-3-ethylcyclopentane-1-carboxylic acid (CAS 1503721-79-6)
- N-(4-Cyano-1H-pyrazol-3-yl)-2,2,2-trifluoroacetamide (CAS 56563-79-2)
- 3-(Benzylamino)-1-(4-methoxyphenyl)azetidin-2-one (CAS 1706575-51-0)
- N-((1H-indazol-4-yl)carbamoyl)benzenesulfonamide (CAS 882748-22-3)
- 4-(4-(Methylthio)phenyl)-1,3-diazaspiro[4.5]dec-3-ene (CAS 84212-20-4)
- endo-Ser39-Tirzepatide (CAS CATO-CPTD788935)
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