3-{[(5-chloro-2-pyridyl)amino]methylidene}-1,1,1-trifluoropentane-2,4-dione CAS 649665-65-6
| CAS No. | 649665-65-6 |
| Molecular Formula | C11H8ClF3N2O2 |
| Molecular Weight | 292.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-{[(5-chloro-2-pyridyl)amino]methylidene}-1,1,1-trifluoropentane-2,4-dione.
CATO supplies 3-{[(5-chloro-2-pyridyl)amino]methylidene}-1,1,1-trifluoropentane-2,4-dione (CAS 649665-65-6), a certified reference material (molecular formula C11H8ClF3N2O2, MW 292.64 g/mol) for analytical method development and quality control.
Structurally, 3-{[(5-chloro-2-pyridyl)amino]methylidene}-1,1,1-trifluoropentane-2,4-dione (C11H8ClF3N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 292.64 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-{[(5-chloro-2-pyridyl)amino]methylidene}-1,1,1-trifluoropentane-2,4-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8ClF3N2O2 |
| Molecular Weight | 292.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related chloro Standards
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Recommended Standards
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- Ethyl 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-cyanoacetate (CAS 923251-81-4)
- 3-(4-Aminophenyl)pyridine-2-carboxylic acid (CAS 1258609-39-0)
- (5,5-Difluoropiperidin-2-yl)methanol hydrochloride (CAS 1823930-16-0)
- 4-Amino-2-chloro-3-methylbenzonitrile (CAS 573768-09-9)
- N,N-[(1-methyl-1H-pyrazol-4-yl)carbonimidoyl]bis-C,C-bis(phenylmethyl) ester (CAS 1610517-97-9)
- (S)-3-Methyl-2-phenylbutanoic Acid (CAS 13490-69-2)
- 2-methoxypyridine-3-sulfonamide (CAS 1566061-98-0)
- 6,6-Dimethyl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonyl chloride (CAS 2091008-99-8)
- Azilsartan Impurity 61 (CAS 856414-36-3)
- 5,5'-(Anthracene-9,10-diylbis(ethyne-2,1-diyl))diisophthalic acid (CAS 1337923-87-1)
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