3-{4-[(3,4-Difluorobenzyl)oxy]phenyl}acrylic acid CAS 649740-48-7
| CAS No. | 649740-48-7 |
| Molecular Formula | C16H12F2O3 |
| Molecular Weight | 290.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-{4-[(3,4-Difluorobenzyl)oxy]phenyl}acrylic acid.
3-{4-[(3,4-Difluorobenzyl)oxy]phenyl}acrylic acid (CAS 649740-48-7) is a high-purity analytical reference standard with the molecular formula C16H12F2O3 and a molecular weight of 290.26 g/mol.
Based on its molecular formula C16H12F2O3, 3-{4-[(3,4-Difluorobenzyl)oxy]phenyl}acrylic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 290.26 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-{4-[(3,4-Difluorobenzyl)oxy]phenyl}acrylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H12F2O3 |
| Molecular Weight | 290.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
Related Difluorobenzyl Standards
- 4-(2,4-Difluorobenzyl)-4,5-dihydrobenzo[f][1,4]oxazepin-3(2H)-one (CAS 1359553-91-5)
- (1-(2,6-Difluorobenzyl)-4-methyl-1H-benzo[d]imidazol-2-yl)methanol (CAS 199594-81-5)
- Ethyl 1-(3,4-difluorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxylate (CAS 1001412-63-0)
- 2-(((3,5-Difluorobenzyl)amino)methyl)-6-ethoxyphenol (CAS 1223880-05-4)
- 1-((3,5-Difluorobenzyl)amino)-3-phenoxypropan-2-ol (CAS 866135-68-4)
- 1-(2,6-Difluorobenzyl)-4-methyl-1H-benzo[d]imidazole-2-carbaldehyde (CAS 199594-83-7)
- 1-(3,4-Difluorobenzyl)-3-(piperidin-4-yl)imidazolidin-2-one (CAS 1243002-01-8)
- 2-(1-(2,3-Difluorobenzyl)-3-oxopiperazin-2-yl)acetic acid (CAS 1033600-07-5)
Recommended Standards
- 3,5-Difluoro-3-(1,3-dioxolan-2-yl)benzophenone (CAS 898759-68-7)
- 5-(2-Fluorophenyl)-2,5-dimethyl-2-(trifluoromethyl)-5,6-dihydro-2H-1,4-oxazin-3-amine (CAS 2641065-06-5)
- 3,4-Difluoro-4-(1,3-dioxolan-2-yl)benzophenone (CAS 898760-78-6)
- Lithium 5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylate (CAS 365996-70-9)
- 3-Ethynyltetrahydrofuran-3-amine (CAS 1934655-69-2)
- 1,1,1-Trifluoroethyl-PEG4-Tos (CAS 1872433-61-8)
- 2-(Piperidin-3-yloxy)acetic acid hydrochloride (CAS 1314936-35-0)
- 1-(2,3-Dimethoxyphenyl)ethanamine (CAS 122670-44-4)
- Dronedarone Impurity 59 (CAS 13422-90-7)
- N1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-N2-(2-morpholinoethyl)oxalamide (CAS 900000-95-5)
- 2-(4-Methylpyrrolidin-2-yl)phenol (CAS 603068-32-2)
- 5-Bromo-2-fluoro-4-methylbenzyl alcohol (CAS 1449008-06-3)
- (2-Phenyloxazol-4-yl)methanamine hydrochloride (CAS 33105-95-2)
- Tau Peptide (301-315) trifluoroacetate salt (CAS 330456-48-9)
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