Ethyl (2Z)-2-chloro-2-[2-(2-fluorophenyl)hydrazin-1-ylidene]acetate CAS 64989-74-8
| CAS No. | 64989-74-8 |
| Molecular Formula | C10H10ClFN2O2 |
| Molecular Weight | 244.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Ethyl (2Z)-2-chloro-2-[2-(2-fluorophenyl)hydrazin-1-ylidene]acetate (CAS 64989-74-8), molecular formula C10H10ClFN2O2 and molecular weight 244.65 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl (2Z)-2-chloro-2-[2-(2-fluorophenyl)hydrazin-1-ylidene]acetate (C10H10ClFN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Ethyl (2Z)-2-chloro-2-[2-(2-fluorophenyl)hydrazin-1-ylidene]acetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10ClFN2O2 |
| Molecular Weight | 244.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 7-Chloro-3-oxo-3,4-dihydro-2H-pyrido-[3,2-b][1,4]thiazine-6-carboxylic acid (CAS 577691-70-4)
- Ethyl (2Z)-2-chloro-2-[2-(4-fluorophenyl)hydrazin-1-ylidene]acetate (CAS 37522-19-3)
- 5-(4-Chloro-3-fluorophenyl)-5-oxovaleric acid (CAS 845790-44-5)
- Ethyl (E)-3-(4-amino-6-chloro-5-fluoropyridin-3-yl)acrylate (CAS 2677884-97-6)
- 2-(5-Amino-1H-indazol-6-yl)propan-2-ol (CAS 2445212-09-7)
- Cisapride (200 mg) (CAS 260779-88-2)
- N-(3-chlorophenyl)-2-((3-cyano-4,6-dimethylpyridin-2-yl)thio)acetamide (CAS 332160-94-8)
- 5-Formyl-1H-pyrazole-3-carboxylic acid (CAS 854699-16-4)
- 2-(1,2-Dithiolan-4-yl)acetic acid (CAS 1026517-37-2)
- ethyl 3-aminothieno[2,3-b]pyridine-2-carboxylate (CAS 52505-46-1)
- n-(5-Fluoro-2-nitrophenyl)methanesulfonamide (CAS 1178407-91-4)
- O-((1-Methyl-1H-indazol-3-yl)methyl)hydroxylamine (CAS 1510287-55-4)
- 4-(Hydroxymethyl)-1,3-thiazole-2-carbaldehyde (CAS 466686-75-9)
- Fragment-[9-31]-Semaglutide (CAS CATO-C4X-2226181)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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