Mesalazine EP Impurity E CAS 65-49-6
| CAS No. | 65-49-6 |
| Molecular Formula | C7H7NO3 |
| Molecular Weight | 153.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Mesalazine EP Impurity E (C7H7NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Mesalazine EP Impurity E (CAS 65-49-6), a pharmacopoeial impurity reference standard (molecular formula C7H7NO3, MW 153.14 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Mesalazine EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7NO3 |
| Molecular Weight | 153.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Mesalazine Standards
Recommended Standards
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- N-[2-(2-Bromo-4-methylphenoxy)ethyl]-3-methoxy-1-propanamine hydrochloride (CAS 1609406-31-6)
- 1-(8-Methoxy-2H-chromene-3-carbonyl)-1H-pyrazole (CAS 318469-32-8)
- 6-Methyl-3-oxo-1h,2h,3h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 91983-61-8)
- 2-Amino-N'-benzoylbenzohydrazide (CAS 28864-27-9)
- 4-Chloro-2-(cyclopropylmethyl)-6-(1-methyl-1H-pyrazol-4-yl)pyrimidine (CAS 1713648-48-6)
- [D-His1]-Semaglutide (CAS CATO-C4X-2226127)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com