2-(3-Nitrofuran-2-yl)-1,3-dioxolane CAS 65019-13-8
| CAS No. | 65019-13-8 |
| Molecular Formula | C7H7NO5 |
| Molecular Weight | 185.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(3-Nitrofuran-2-yl)-1,3-dioxolane (C7H7NO5) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-(3-Nitrofuran-2-yl)-1,3-dioxolane (CAS 65019-13-8) is a high-purity analytical reference standard with the molecular formula C7H7NO5 and a molecular weight of 185.13 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(3-Nitrofuran-2-yl)-1,3-dioxolane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7NO5 |
| Molecular Weight | 185.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 1 |
Related Nitrofuran Standards
- Ethyl 5-nitrofuran-2-carboxylate (CAS 943-37-3)
- 2-(5-nitrofuran-2-yl)-1,3,4-oxadiazole (CAS 89488-64-2)
- 3-(5-Nitrofuran-2-yl)-4H-1,2,4-triazole (CAS 5019-55-6)
- 1-Methyl-3-(5-nitrofuran-2-yl)-1H-pyrazole (CAS 61621-23-6)
- 3-(5-Nitrofuran-2-yl)isoxazol-5-amine (CAS 33857-00-0)
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- 5-(5-Nitrofuran-2-yl)-1,3,4-oxadiazol-2-amine (CAS 3775-55-1)
- 5-(5-Nitrofuran-2-yl)-1,3,4-oxadiazol-2(3H)-one (CAS 2122-86-3)
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- 2-Benzyl-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione (CAS 37799-00-1)
- 2-Hydroxy-3-phenylbutanoic acid (CAS 91061-47-1)
- Phenylephrine Impurity 12 (CAS CATO-C4X-146712)
- Semaglutide impurity 268 (CAS CATO-C4X-2226268)
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