6-Chloro-4-oxo-3,4-dihydrophthalazine-1-carboxylic acid CAS 65095-35-4
| CAS No. | 65095-35-4 |
| Molecular Formula | C9H5ClN2O3 |
| Molecular Weight | 224.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-4-oxo-3,4-dihydrophthalazine-1-carboxylic acid.
6-Chloro-4-oxo-3,4-dihydrophthalazine-1-carboxylic acid (CAS 65095-35-4) is a high-purity analytical reference standard with the molecular formula C9H5ClN2O3 and a molecular weight of 224.60 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 6-Chloro-4-oxo-3,4-dihydrophthalazine-1-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 224.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5ClN2O3 |
| Molecular Weight | 224.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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- 6-Chloro-3-nitroquinolin-4-ol (CAS 101861-61-4)
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Recommended Standards
- 6-Chloro-4-oxo-1,4-dihydroquinazoline-2-carboxylic acid (CAS 480451-49-8)
- 6-Chloro-4-oxo-3,4-dihydroquinazoline-7-carboxylic acid (CAS 758710-85-9)
- 6-Chloro-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxylic acid, 97% (CAS 959277-17-9)
- 6-Chloro-4-oxo-4H-chromene-3-carboxylic acid (CAS 51085-92-8)
- 2,2-Anhydrothymidine (CAS 22423-26-3)
- 4-Amino-3,3-dimethyl-piperidine-1-carboxylic acid tert-butyl ester hydrochloride (CAS 1965310-21-7)
- 1-(1-Methyl-1H-benzo[d][1,2,3]triazol-7-yl)ethanone (CAS 1545330-22-0)
- 2-(Thiophen-2-ylsulfanyl)-ethanol (CAS 55697-86-4)
- Ethyl 4-cyano-5-methoxy-2-nitrobenzoate (CAS 1807034-22-5)
- 7-Chloro-2,2,4-trimethyl-1,2-dihydroquinoline (CAS 1810-73-7)
- Finerenone Impurity 78 (CAS CATO-C4X-288078)
- (R)-N,N'-[1,1'-Binaphthalene]-2,2'-diylbis[2-(diphenylphosphino)benzamide] (CAS 298695-62-2)
- 5-(Benzyloxy)-3-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine (CAS 1262133-29-8)
- Liraglutide (13-21) TFA Salt (CAS CATO-C4X-19928)
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