| CAS No. | 651-12-7 |
| Molecular Formula | C8H4Br2F4 |
| Molecular Weight | 335.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 335.92 g/mol gives 1,4-Bis[bromo(difluoro)methyl]benzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1,4-Bis[bromo(difluoro)methyl]benzene (CAS 651-12-7), a certified reference material (molecular formula C8H4Br2F4, MW 335.92 g/mol) for analytical method development and quality control.
The molecular framework of 1,4-Bis[bromo(difluoro)methyl]benzene (C8H4Br2F4) is characterized by fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
| Molecular Formula | C8H4Br2F4 |
| Molecular Weight | 335.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |