1,4-Bis[bromo(difluoro)methyl]benzene CAS 651-12-7

Purity 97%+In StockPharmaceutical Standards
CAS No.651-12-7
Molecular FormulaC8H4Br2F4
Molecular Weight335.92 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1,4-Bis[bromo(difluoro)methyl]benzene CAS 651-12-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 335.92 g/mol gives 1,4-Bis[bromo(difluoro)methyl]benzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 1,4-Bis[bromo(difluoro)methyl]benzene (CAS 651-12-7), a certified reference material (molecular formula C8H4Br2F4, MW 335.92 g/mol) for analytical method development and quality control.

The molecular framework of 1,4-Bis[bromo(difluoro)methyl]benzene (C8H4Br2F4) is characterized by fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H4Br2F4
Molecular Weight335.92 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF/Br-containing

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