N-(Piperidin-3-ylmethyl)isoquinolin-5-amine hydrochloride CAS 651307-08-3
| CAS No. | 651307-08-3 |
| Molecular Formula | C15H19N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(Piperidin-3-ylmethyl)isoquinolin-5-amine hydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(Piperidin-3-ylmethyl)isoquinolin-5-amine hydrochloride (CAS 651307-08-3), molecular formula C15H19N3HCl and molecular weight 277.80 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(Piperidin-3-ylmethyl)isoquinolin-5-amine hydrochloride (C15H19N3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H19N3 HCl |
| Molecular Weight | 277.80 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 1000339-76-3 Ethyl 2-(Piperidin-1-yl)-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate ethyl 2-(piperidin-1-yl)-4-trifluoromethyl-1,3-thiazole-5-carboxylate ethyl 2-piperidin-1-yl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate (CAS 1000339-76-3)
- 2-(Piperidin-1-yl)-4-(trifluoromethyl)thiazole-5-carboxylic acid (CAS 1000339-77-4)
- Benzyl 2-(piperidin-4-yl)acetate hydrochloride (CAS 1000872-47-8)
- n-(Piperidin-3-ylmethyl)morpholine-4-carboxamide (CAS 1000941-33-2)
- 1000958-55-3 4-Ethyl-1-[2-(piperidin-4-yl)ethyl]piperidine DTXSID60649257 (CAS 1000958-55-3)
- 5-(Piperidin-2-yl)pyridin-2-amine (CAS 100133-12-8)
- 5-(Piperidin-1-ylmethyl)pyrimidine-2,4(1H,3H)-dione (CAS 100133-53-7)
- 1-methyl-5-(piperidin-1-ylcarbonyl)-1H-pyrazol-4-amine (CAS 1001500-82-8)
Recommended Standards
- 4-(hydroxymethyl)piperidin-2-one (CAS 53611-47-5)
- n-(2-Methylpentan-3-yl)-4-(methylthio)aniline (CAS 1157598-15-6)
- 2-Bromo-6-(difluoromethyl)-5-iodonicotinaldehyde (CAS 1806909-24-9)
- 2-(3,4-Dimethylphenoxy)pyridine-4-carbonitrile (CAS 1016822-48-2)
- 2-O-α-D-Glucopyranosyl-D-galactopyranose (CAS 7368-73-2)
- Ethyl (R)-6-azaspiro[2.5]Octane-1-carboxylate (CAS 1539277-96-7)
- 5-Bromo-3-hydroxy-2-methoxybenzoic acid (CAS 107189-07-1)
- Salbutamol Impurity 189 (CAS CATO-C4X-1176189)
- Methyl 4-chloro-6-(difluoromethyl)nicotinate (CAS 1805196-45-5)
- Tirzepatide Impurity 50 (CAS CATO-C4X-324050)
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