7-chloroquinoline-2-carboxamide CAS 65147-97-9
| CAS No. | 65147-97-9 |
| Molecular Formula | C10H7ClN2O |
| Molecular Weight | 206.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
7-chloroquinoline-2-carboxamide (CAS 65147-97-9) is a high-purity analytical reference standard with the molecular formula C10H7ClN2O and a molecular weight of 206.63 g/mol.
The molecular framework of 7-chloroquinoline-2-carboxamide (C10H7ClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN2O |
| Molecular Weight | 206.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related chloroquinoline Standards
- 8-Chloroquinoline-2-carboxamide (CAS 1070370-89-6)
- 7-Chloroquinoline-3-carboxamide (CAS 1296950-49-6)
- 6-Chloroquinoline-3-carboxamide (CAS 1296950-87-2)
- 4-Chloroquinoline-7-carboxamide (CAS 178984-42-4)
- 2-Chloroquinoline-6-carboxamide (CAS 1823476-06-7)
- 5-Chloroquinoline-8-carboxamide (CAS 1824025-22-0)
- 2-Chloroquinoline-3-carboxamide (CAS 73776-21-3)
- 2-Chloroquinoline-4-carboxamide (CAS 4295-16-3)
Recommended Standards
- 7-Chloro-1-naphthoic acid (CAS 58926-30-0)
- 8-Chloro-1-naphthoic Acid (CAS 4537-00-2)
- 6-Hydroxy-2-naphthoyl chloride (CAS 215959-99-2)
- 8-Chloro-6-methyl-1,7-naphthyridine-3-carbaldehyde (CAS 2692638-21-2)
- 1-(5-(Tert-butyl)benzo[d]oxazol-2-yl)piperidin-4-amine (CAS 1035840-48-2)
- Methyl 8-nitroquinoxaline-6-carboxylate (CAS 1706445-46-6)
- 5-(Thiophen-3-yl)pyridin-2-amine (CAS 892282-90-5)
- 3-(4-Fluorophenyl)-1H-1,2,4-triazol-5(4H)-one (CAS 111396-66-8)
- 4-(tert-Butoxy)-2,5-difluoro-3-methylpyridine (CAS 169749-84-2)
- 3-(2-(Allylthio)pyrimidin-4-yl)-1-(p-tolyl)pyridazin-4(1H)-one (CAS 478077-70-2)
- tert-Butyl 6-hydroxy-2-azabicyclo[2.2.1]heptane-2-carboxylate (CAS 207405-59-2)
- 1-(But-3-en-1-yl)azetidine (CAS 69416-77-9)
- (1-(Benzo[d]oxazol-2-yl)pyrrolidin-2-yl)methanol (CAS 1251268-90-2)
- 59880-97-6 Chemotactic peptide F-Met-Leu-Phe L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- N-Formyl-L-methionyl-L-leucyl-L-phenylalanine N-Formyl-Met-Leu-Phe N-Formylmethionine leucyl-phenylalanine fMLF fMLP (misnomer but widely used) (CAS 59880-97-6)
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