2-(4-Hydroxyphenyl)-6-(trifluoromethyl)pyrimidin-4(1H)-one CAS 651722-96-2
| CAS No. | 651722-96-2 |
| Molecular Formula | C11H7F3N2O2 |
| Molecular Weight | 256.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-Hydroxyphenyl)-6-(trifluoromethyl)pyrimidin-4(1H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(4-Hydroxyphenyl)-6-(trifluoromethyl)pyrimidin-4(1H)-one (CAS 651722-96-2), a certified reference material (molecular formula C11H7F3N2O2, MW 256.18 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-(4-Hydroxyphenyl)-6-(trifluoromethyl)pyrimidin-4(1H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 256.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H7F3N2O2 |
| Molecular Weight | 256.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Hydroxyphenyl Standards
- 1,3-Bis(4-hydroxyphenyl)propane-1,3-dione (CAS 33976-92-0)
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- 1-(2-Hydroxyphenyl)-3-(4-methoxyphenyl)propan-1-one (CAS 56202-01-8)
- 1-(4-Hydroxyphenyl)-3-(4-methoxyphenyl)propan-1-one (CAS 66760-72-3)
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Recommended Standards
- 1-Phenyl-5-(trifluoromethyl)pyrazole-4-carboxylic Acid (CAS 98534-81-7)
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- 1-Phenyl-5-(trifluoromethyl)-1h-pyrazole-3-carboxylic acid (CAS 497833-13-3)
- 2-Bromo-4,6-diisopropylaniline (CAS 79069-42-4)
- (E)-4-((2-(furan-2-yl)ethyl)amino)-4-oxobut-2-enoic acid (CAS 887833-39-8)
- (2E)-3-(3-Methylphenyl)-1-(4-methylphenyl)prop-2-en-1-one (CAS 52182-33-9)
- 1-(4-Isopropylphenyl)-1h-pyrazole-3-carboxylic acid (CAS 1152535-62-0)
- 1-(2-Propyn-1-yl)piperidine (CAS 5799-75-7)
- 1-(3-Bromophenyl)-2-phenylpropan-2-amine hydrochloride (CAS 1354951-45-3)
- 2-(3-Fluoroazetidin-3-yl)acetonitrile (CAS 2091482-01-6)
- 2,2’-Bis(di-p-tolylphosphino)-1,1’-binaphthyl (CAS 153305-67-0)
- 1-(2-Aminoethyl)-3,4-dihydroisoquinoline-6,7-diol (CAS 748760-14-7)
- 3,8-Diphenylpyrazolo[5,1-c][1,2,4]triazin-4-amine (CAS 1306738-72-6)
- His-Cyclic-Semaglutide (CAS CATO-C4X-2226182)
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