Methyl 2-Bromo-4-fluorobenzoate CAS 653-92-9
| CAS No. | 653-92-9 |
| Molecular Formula | C8H6BrFO2 |
| Molecular Weight | 233.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Methyl 2-Bromo-4-fluorobenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Methyl 2-Bromo-4-fluorobenzoate (CAS 653-92-9), molecular formula C8H6BrFO2 and molecular weight 233.03 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, Methyl 2-Bromo-4-fluorobenzoate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 233.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H6BrFO2 |
| Molecular Weight | 233.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |
Related Methyl Standards
- 2-Bromo-4-fluoro-5-methylbenzoic acid (CAS 1003709-39-4)
- 2-Bromo-4-fluoro-6-methylbenzoic Acid (CAS 1003709-47-4)
- 2-Bromo-5-fluoro-4-methylbenzoic acid (CAS 1003709-54-3)
- 3-Bromo-5-fluoro-2-methoxybenzaldehyde (CAS 1009093-60-0)
- 1-(5-Bromo-3-fluoro-2-hydroxyphenyl)ethan-1-one (CAS 1089706-28-4)
- 4-Bromo-2-fluorophenylacetic Acid (CAS 114897-92-6)
- 3-Bromo-2-fluoro-4-methoxybenzaldehyde (CAS 1155877-70-5)
- 3-Bromo-2-fluoro-6-methoxybenzaldehyde (CAS 1160653-94-0)
Recommended Standards
- Methyl 2-bromo-3-fluorobenzoate (CAS 647020-71-1)
- Methyl 2-Bromo-5-fluorobenzoate (CAS 6942-39-8)
- 6-Bromo-7-fluoro-2,3-dihydro-1,4-benzodioxin (CAS 69464-29-5)
- Methyl 2-Bromo-6-fluorobenzoate (CAS 820236-81-5)
- tert-butyl N-[4-(2,2-dimethylhydrazin-1-yl)cyclohexyl]carbamate (CAS 1557968-78-1)
- 3-[(7-chloroquinolin-4-yl)sulfanyl]propanoic acid (CAS 874487-43-1)
- 5-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)-2-fluorobenzoic acid (CAS 1341822-36-3)
- 6-Bromo-2-chlorothiazolo[4,5-b]pyridin-5(4H)-one (CAS 2766293-33-6)
- 2-((3-(3-Bromophenyl)-1H-1,2,4-triazol-5-yl)thio)-N-(2,4,6-trichlorophenyl)acetamide (CAS 332127-67-0)
- 34469-63-1 Flavin mononucleotide semiquinone Riboflavin 5'-(dihydrogen phosphate), radical ion(1-) Fmn semiquinone (CAS 34469-63-1)
- (R)-1-benzyl-N-methylpiperidin-3-amine (CAS 1354011-07-6)
- DNQX Disodium Salt (CAS 1312992-24-7)
- 1-Benzyl-5-phenyl-1H-pyrazole-3-carboxylic acid (CAS 1020239-97-7)
- [D-Glu]3-Semaglutide (CAS CATO-C4X-2226253)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com