8-(4-Methoxybenzylidene)-4-(4-methoxyphenyl)-3,4,5,6,7,8-hexahydroquinazoline-2(1H)-thione CAS 65331-30-8

Purity 97%+In StockPharmaceutical Standards
CAS No.65331-30-8
Molecular FormulaC23H24N2O2S
Molecular Weight392.51 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

8-(4-Methoxybenzylidene)-4-(4-methoxyphenyl)-3,4,5,6,7,8-hexahydroquinazoline-2(1H)-thione CAS 65331-30-8 chemical structure

Description

Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 8-(4-Methoxybenzylidene)-4-(4-methoxyphenyl)-3,4,5,6,7,8-hexahydroquinazoline-2(1H)-thione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 392.51 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

CATO supplies 8-(4-Methoxybenzylidene)-4-(4-methoxyphenyl)-3,4,5,6,7,8-hexahydroquinazoline-2(1H)-thione (CAS 65331-30-8), a certified reference material (molecular formula C23H24N2O2S, MW 392.51 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 8-(4-Methoxybenzylidene)-4-(4-methoxyphenyl)-3,4,5,6,7,8-hexahydroquinazoline-2(1H)-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC23H24N2O2S
Molecular Weight392.51 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1975
Nitrogen Atoms2
Sulfur Atoms1

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