2-[(2-Chloroacetyl)(methyl)amino]acetic acid CAS 65332-01-6
| CAS No. | 65332-01-6 |
| Molecular Formula | C5H8ClNO3 |
| Molecular Weight | 165.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-[(2-Chloroacetyl)(methyl)amino]acetic acid (CAS 65332-01-6), a certified reference material (molecular formula C5H8ClNO3, MW 165.57 g/mol) for analytical method development and quality control.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, 2-[(2-Chloroacetyl)(methyl)amino]acetic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 165.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H8ClNO3 |
| Molecular Weight | 165.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloroacetyl Standards
- N-Chloroacetyl-DL-alanine (CAS 1190-32-5)
- Ethyl (2-Chloroacetyl)carbamate (CAS 6092-47-3)
- 3-(2-Chloroacetyl)-1-ethylurea (CAS 4791-24-6)
- N'-(2-chloroacetyl)propionohydrazide (CAS 38090-72-1)
- 4-(Chloroacetyl)morpholine (CAS 1440-61-5)
- N-(2-Chloroacetyl)-2-methylpropanamide (CAS 726155-02-8)
- (S)-4-(2-chloroacetyl)oxazolidin-2-one (CAS 244793-72-4)
- 3-(chloroacetyl)-1,3-oxazolidin-2-one (CAS 460313-68-2)
Recommended Standards
- (R)-2-(2-Chloroacetamido)propanoic acid (CAS 67206-15-9)
- 2-Chloro-N-(2-methoxyacetyl)acetamide (CAS 852840-60-9)
- 3-(2-Chloroacetamido)propanoic acid (CAS 4596-38-7)
- 6-Chloro-1,3,5-triazine-2,4-dicarbonitrile (CAS 80587-76-4)
- N-{2-[4-Amino-3-(trifluoromethyl)phenoxy]ethyl}-N,N-diethylamine dihydrochloride (CAS 1185297-54-4)
- N-(5-Iodo-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-2-yl)pivalamide (CAS 137281-11-9)
- 2-(4-Butylthiophen-2-yl)-5,5-dimethyl-1,3,2-dioxaborinane (CAS 919079-92-8)
- N-(8-Methoxy-2-oxo-2H-chromen-3-yl)acetamide (CAS 33259-48-2)
- Sitoindoside I (CAS 18749-71-8)
- [S-(R,R)]-[2-Hydroxy-1-[(methoxyamino)carbonyl]propyl]-carbamic Acid 1,1-Dimethylethyl Ester (CAS 80543-39-1)
- Urapidil Impurity 27 (CAS 31737-09-4)
- (3-Butoxy-4-methylphenyl)(methyl)sulfane (CAS 1379369-46-6)
- 2-(2-Aminobutan-2-yl)-6-(tert-butyl)pyrimidin-4(3H)-one hydrochloride (CAS 1354952-18-3)
- Semaglutide impurity 277 (CAS CATO-C4X-2226277)
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