6-Bromo-4-chloroquinoline CAS 65340-70-7
| CAS No. | 65340-70-7 |
| Molecular Formula | C9H5BrClN |
| Molecular Weight | 242.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution, 6-Bromo-4-chloroquinoline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 242.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
6-Bromo-4-chloroquinoline (CAS 65340-70-7) is a high-purity analytical reference standard with the molecular formula C9H5BrClN and a molecular weight of 242.50 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5BrClN |
| Molecular Weight | 242.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 8-Bromo-3-chloroisoquinoline (CAS 1029720-63-5)
- 7-Bromo-3-chloroisoquinoline (CAS 1029720-65-7)
- 5-Bromo-3-chloroisoquinoline (CAS 1029720-67-9)
- 6-Bromo-7-chloroisoquinoline (CAS 1036712-54-5)
- 2-Bromo-7-chloroquinoline (CAS 1044764-18-2)
- 6-Bromo-2-chloronicotinic acid (CAS 1060815-67-9)
- 8-Bromo-5-chloroquinoline (CAS 1154741-20-4)
- 1-Bromo-6-chloroisoquinoline (CAS 1196146-81-2)
Recommended Standards
- 6-Bromo-3-chloroisoquinoline (CAS 552331-06-3)
- 7-Bromo-1-chloroisoquinoline, 97% (CAS 215453-51-3)
- 6-Bromo-1-chloroisoquinoline, 97% (CAS 205055-63-6)
- 7-Bromo-4-chloroquinoline, 97% (CAS 75090-52-7)
- (S)-1-Cbz-2-methylpiperazine (CAS 923565-98-4)
- 2-Hydroxy-1-[4-(2-hydroxyethyl)phenyl]-2-methylpropan-1-one (CAS 106797-54-0)
- Calcium α-D-heptagluconate dihydrate (CAS 10030-53-2)
- 5-(4-Bromophenyl)-2-(methylthio)-1-phenyl-1H-imidazole (CAS 1206986-17-5)
- Malonamide (CAS 108-13-4)
- Cyclopropyl(4-(trifluoromethyl)phenyl)methanamine hydrochloride (CAS 1159825-60-1)
- 4-((4-((Tert-butoxycarbonyl)amino)piperidin-1-yl)methyl)benzoic acid (CAS 653593-70-5)
- Methyl 4-(difluoromethoxy)-5-methoxy-1h-indole-2-carboxylate (CAS 926199-54-4)
- 2-(2-Cyano-5-(difluoromethyl)-4-nitropyridin-3-yl)acetic acid (CAS 1805183-08-7)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
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