2-Fluoro-isonicotinoyl chloride CAS 65352-95-6

Purity 97%+In StockPharmaceutical Standards
CAS No.65352-95-6
Molecular FormulaC6H3ClFNO
Molecular Weight159.55 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Fluoro-isonicotinoyl chloride CAS 65352-95-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 159.55 g/mol gives 2-Fluoro-isonicotinoyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Fluoro-isonicotinoyl chloride (CAS 65352-95-6), molecular formula C6H3ClFNO and molecular weight 159.55 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-Fluoro-isonicotinoyl chloride (C6H3ClFNO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

CATO manufactures 2-Fluoro-isonicotinoyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC6H3ClFNO
Molecular Weight159.55 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1975
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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