1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(prop-2-yn-1-yloxy)pyrimidine-2,4(1H,3H)-dione CAS 65367-85-3
| CAS No. | 65367-85-3 |
| Molecular Formula | C12H14N2O6 |
| Molecular Weight | 282.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(prop-2-yn-1-yloxy)pyrimidine-2,4(1H,3H)-dione (C12H14N2O6) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(prop-2-yn-1-yloxy)pyrimidine-2,4(1H,3H)-dione (CAS 65367-85-3) is a high-purity analytical reference standard with the molecular formula C12H14N2O6 and a molecular weight of 282.25 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(prop-2-yn-1-yloxy)pyrimidine-2,4(1H,3H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14N2O6 |
| Molecular Weight | 282.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 2 |
Recommended Standards
- (3Z)-3-[(4-Hydroxy-3-nitrophenyl)methylidene]-2,3-dihydro-1H-indol-2-one (CAS 866038-46-2)
- 1-(3-Nitrobenzyl)indoline-2,3-dione (CAS 346442-46-4)
- (3-Aminobenzofuran-2-yl)(2-nitrophenyl)methanone (CAS 310462-59-0)
- 1-(4-Nitrobenzyl)indoline-2,3-dione (CAS 31541-33-0)
- 5-(6-Methoxy-4-methylpyridin-3-yl)thiophene-2-carbaldehyde (CAS 1225058-56-9)
- N-(Quinolin-3-ylmethyl)-N-(4-sulfamoylphenyl)formamide (CAS 62294-91-1)
- 7-Chloro-2,3-dihydro-1,4-benzodioxine-6-thiol (CAS 1152581-30-0)
- N-methyl-1-(6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methanamine (CAS 1892552-39-4)
- (R)-1-(3-fluoro-5-methylphenyl)propan-1-amine (CAS 1023289-46-4)
- Roflumilast Impurity 12 (CAS CATO-C4X-204712)
- 2-cyclohexylmorpholine (CAS 1251196-25-4)
- Ethyl 2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-2,2-difluoroacetate (CAS 478043-86-6)
- 3,5-Dimethyl-4-isopropoxyphenylboronic Acid (CAS 849062-16-4)
- D-[Ser]8-Semaglutide (CAS CATO-CPTD788632)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com