8-Hydroxy-7-methoxyisoquinoline-1-carbonitrile CAS 654077-41-5
| CAS No. | 654077-41-5 |
| Molecular Formula | C11H8N2O2 |
| Molecular Weight | 200.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 8-Hydroxy-7-methoxyisoquinoline-1-carbonitrile (CAS 654077-41-5), a certified reference material (molecular formula C11H8N2O2, MW 200.19 g/mol) for analytical method development and quality control.
The molecular framework of 8-Hydroxy-7-methoxyisoquinoline-1-carbonitrile (C11H8N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 8-Hydroxy-7-methoxyisoquinoline-1-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8N2O2 |
| Molecular Weight | 200.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 2 |
Related Hydroxy Standards
- Ethyl 2-hydroxy-2-(2-oxodihydro-2H-pyran-3(4H)-ylidene)acetate (CAS 110977-72-5)
- 2-Hydroxy-7-methoxyquinoline-3-carbonitrile (CAS 116704-99-5)
- Methyl 2-(5-hydroxy-1-(2-hydroxyethyl)-1H-pyrazol-4-yl)acetate (CAS 1365959-61-0)
- 4-hydroxy-6-methoxyquinoline-3-carbonitrile (CAS 13669-61-9)
- 4-Hydroxy-6-methoxyquinoline-7-carbonitrile (CAS 1817630-46-8)
- 2-(2-Hydroxy-5-methoxybenzylidene)malononitrile (CAS 771574-72-2)
- 2-(2-Hydroxy-6-methoxybenzylidene)malononitrile (CAS 771558-71-5)
- 2-(4-Hydroxy-2-methoxybenzylidene)malononitrile (CAS 771564-84-2)
Recommended Standards
- 8-Formyl-1-naphthoic acid (CAS 5811-87-0)
- 8-Methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile (CAS 71083-71-1)
- 8-Acetylquinoxaline-5-carbaldehyde (CAS 89334-33-8)
- 9-Hydroxy-1,8-naphthalide (CAS 5656-90-6)
- 1-(Cyclohex-1-en-1-yl)cyclopropane-1-sulfonamide (CAS 669008-30-4)
- 6-Fluoro-3-hydroxybenzo[b]thiophene-2-carboxylic acid (CAS 1555552-10-7)
- 2-(4-Fluoro-phenyl)-pyrrolidine oxalic acid salt (CAS 1197226-82-6)
- (1-(6-(Trifluoromethyl)pyridin-2-yl)piperidin-4-yl)methanol (CAS 1086376-64-8)
- Piperazine Impurity 4 (CAS 1293489-64-1)
- 1,2,4-Oxadiazole-5-carboxylic acid (CAS 499770-64-8)
- ethyl 7-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate (CAS 867034-10-4)
- 5-(Benzyloxy)-2-(tert-butyl)pyridine (CAS 1196074-15-3)
- 4-Methyl-2-(1H-pyrrol-1-yl)thiazole-5-carbaldehyde (CAS 1774901-15-3)
- Acetyl Hexapeptide-38 (CAS 1400634-44-7)
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