2-(Ethylsulfonyl)-5-(trifluoromethyl)-1,3,4-thiadiazole CAS 65439-35-2
| CAS No. | 65439-35-2 |
| Molecular Formula | C5H5F3N2O2S2 |
| Molecular Weight | 246.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(Ethylsulfonyl)-5-(trifluoromethyl)-1,3,4-thiadiazole (CAS 65439-35-2) is a high-purity analytical reference standard with the molecular formula C5H5F3N2O2S2 and a molecular weight of 246.23 g/mol.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 2-(Ethylsulfonyl)-5-(trifluoromethyl)-1,3,4-thiadiazole is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 246.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5F3N2O2S2 |
| Molecular Weight | 246.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Ethylsulfonyl Standards
- 1-(Ethylsulfonyl)-3-(trifluoromethyl)piperazine (CAS 2287228-03-7)
- 4-Ethylsulfonyl-2-nitroanisole (CAS 51572-44-2)
- 4-((Ethylsulfonyl)methyl)-1,2-dimethyl-5-nitro-1H-imidazole (CAS 1707568-09-9)
- Ethyl 2-(ethylsulfonyl)pyrimidine-5-carboxylate (CAS 858269-11-1)
- 5-Ethylsulfonyl-2-methoxy-benzoic acid (CAS 4840-63-5)
- 2-((4-(Ethylsulfonyl)-1-methyl-1H-pyrazol-5-yl)oxy)acetic acid (CAS 1774896-91-1)
- 4-(Ethylsulfonyl)-1-naphthaldehyde (CAS 282728-20-5)
- 3-(Ethylsulfonyl)bromobenzene (CAS 153435-82-6)
Recommended Standards
- 2-(ethylamino)-N-[2-(trifluoromethyl)phenyl]acetamide (CAS 863411-08-9)
- 2-(propylamino)-N-(2,3,4-trifluorophenyl)acetamide (CAS 796106-58-6)
- 2-(Benzyloxy)-5-fluorobenzoic acid (CAS 847256-14-8)
- 2-[(4-Fluorobenzyl)oxy]benzoic acid (CAS 396-11-2)
- 4-Bromo-3-chloro-6-indazolecarboxylic Acid methyl ester (CAS 885523-57-9)
- 5-((7-(TRIFLUOROMETHYL)-5-(4-(TRIFLUOROMETHYL)PHENYL)PYRAZOLO[1,5-A]PYRIMIDIN-3-YL)ETHYNYL)PYRIDIN-2-AMINE (CAS 911115-16-7)
- Methyl cis-4-{[(tert-butoxy)carbonyl]amino}oxolane-3-carboxylate (CAS 1310708-60-1)
- Ethyl 5-amino-1-((2S,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-imidazole-4-carboxylate (CAS 53294-13-6)
- 5-(Tert-butyl)-4,5,6,7-tetrahydrobenzo[d]oxazol-2-amine (CAS 1351387-05-7)
- 3-(2-Hydroxy-3-methoxy-propoxy)-benzoic acid (CAS 3478-07-7)
- (3,5-Dimethyl-4-((phenylsulfonyl)methyl)-1H-pyrazol-1-yl)(pyridin-3-yl)methanone (CAS 321848-15-1)
- 3-(prop-2-en-1-yl)piperidine (CAS 1260880-04-3)
- N-(3-Cyanothiophen-2-yl)-2-(4-(methylthio)phenyl)acetamide (CAS 941971-30-8)
- Liraglutide(14-22)TFA Salt (CAS CATO-C4X-199212)
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