3-Chloro-4-phenyl-4H-cyclopenta[c]cinnoline-1-carboxylic acid CAS 65533-82-6
| CAS No. | 65533-82-6 |
| Molecular Formula | C18H11ClN2O2 |
| Molecular Weight | 322.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Chloro-4-phenyl-4H-cyclopenta[c]cinnoline-1-carboxylic acid is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Chloro-4-phenyl-4H-cyclopenta[c]cinnoline-1-carboxylic acid (CAS 65533-82-6), molecular formula C18H11ClN2O2 and molecular weight 322.75 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Chloro-4-phenyl-4H-cyclopenta[c]cinnoline-1-carboxylic acid (C18H11ClN2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Chloro-4-phenyl-4H-cyclopenta[c]cinnoline-1-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H11ClN2O2 |
| Molecular Weight | 322.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
- 4-(4-Chlorophenoxy)-6-phenylfuro[2,3-d]pyrimidine (CAS 672925-52-9)
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- Ethyl 3-(5-(chlorosulfonyl)thiophen-2-yl)-1,2,4-oxadiazole-5-carboxylate (CAS 388088-70-8)
- 2-(4-Chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)isoquinolin-1(2H)-one (CAS 113293-11-1)
- N-Isopropylaniline-d (CAS 67699-91-6)
- Ethyl 5-((tert-butoxycarbonyl)amino)-1H-pyrrole-2-carboxylate (CAS 547762-37-8)
- (3-Chloro-2-fluorobenzyl)(3,4-difluorophenyl)sulfane (CAS 1443304-25-3)
- Benzenesulfonamide, 3-nitro-N-phenyl-4-(phenylamino)- (CAS 5124-25-4)
- (S)-4-(((9H-fluoren-9-yl)methoxy)carbonyl)piperazine-2-carboxylic acid (CAS 1217628-46-0)
- 2-Bromo-N,N-dihexylacetamide (CAS 204575-47-3)
- Benzyl ((1R,2R,3R,5R)-2-((tert-butyldimethylsilyl)oxy)bicyclo[3.1.0]Hexan-3-yl)carbamate (CAS 2306253-90-5)
- [4-(ethanesulfonyl)-3-fluorophenyl]methanamine hydrochloride (CAS 1803611-51-9)
- 2-((5-Amino-1,3,4-thiadiazol-2-yl)thio)-N-(ethylcarbamoyl)propanamide (CAS 871804-03-4)
- C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 127869-51-6)
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