4-Nitro-N-(p-tolyl)-2-(trifluoromethyl)aniline CAS 65592-56-5
| CAS No. | 65592-56-5 |
| Molecular Formula | C14H11F3N2O2 |
| Molecular Weight | 296.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Nitro-N-(p-tolyl)-2-(trifluoromethyl)aniline is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-Nitro-N-(p-tolyl)-2-(trifluoromethyl)aniline (CAS 65592-56-5), a certified reference material (molecular formula C14H11F3N2O2, MW 296.24 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-Nitro-N-(p-tolyl)-2-(trifluoromethyl)aniline is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 296.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11F3N2O2 |
| Molecular Weight | 296.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 4-(tert-Butyl)-2-methylpyridine (CAS 97691-20-8)
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- 4,5-Dimethyl-2-isopropoxyphenylboronic acid (CAS 2121514-40-5)
- 4-Isopropyl-4-methylpyrrolidin-2-one (CAS 1217862-71-9)
- Semaglutide impurity 27 (CAS CATO-C4X-222627)
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