4-(3,4-Dihydroxyphenyl)-5-hydroxyisoquinolin-1(2H)-one CAS 656234-48-9
| CAS No. | 656234-48-9 |
| Molecular Formula | C15H11NO4 |
| Molecular Weight | 269.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(3,4-Dihydroxyphenyl)-5-hydroxyisoquinolin-1(2H)-one (CAS 656234-48-9) is a high-purity analytical reference standard with the molecular formula C15H11NO4 and a molecular weight of 269.25 g/mol.
Structurally, 4-(3,4-Dihydroxyphenyl)-5-hydroxyisoquinolin-1(2H)-one (C15H11NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 269.25 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(3,4-Dihydroxyphenyl)-5-hydroxyisoquinolin-1(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H11NO4 |
| Molecular Weight | 269.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
Related Dihydroxyphenyl Standards
- 2-(3,4-Dihydroxyphenyl)-6-hydroxy-4H-chromen-4-one (CAS 263407-43-8)
- 1-(2,4-Dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one (CAS 104236-78-4)
- 1-(2,4-Dihydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (CAS 13351-10-5)
- 1-(2,5-Dihydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (CAS 6342-92-3)
- 1-(3,4-Dihydroxyphenyl)-2-((1-methyl-1H-tetrazol-5-yl)thio)ethan-1-one (CAS 401590-85-0)
- (E)-1-(2,4-Dihydroxyphenyl)-3-(3,5-dihydroxyphenyl)prop-2-en-1-one (CAS 75514-30-6)
- 3-(2,6-Dihydroxyphenyl)-7-hydroxy-5-methylisobenzofuran-1(3H)-one (CAS 479350-63-5)
- 4842-48-2 [R,(-)]-1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)-1-propanone (CAS 4842-48-2)
Recommended Standards
- 3-Methyl-2-(2-(5-nitrofuran-2-yl)vinyl)benzofuran (CAS 89266-61-5)
- 4-(4-Nitrophenyl)isochroman-3-one (CAS 1980040-06-9)
- 3-Benzyl-2-oxo-2,3-dihydrobenzo[d]oxazole-5-carboxylic acid (CAS 932543-44-7)
- 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-5-vinyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one (CAS 847651-93-8)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-morpholinophenyl)acetamide (CAS 685108-01-4)
- Ethyl 3-({[(benzyloxy)imino]methyl}amino)-4-methoxythieno[2,3-b]pyridine-2-carboxylate (CAS 341966-63-0)
- (S)-2-Amino-N-(2-chlorobenzyl)-N-isopropylpropanamide (CAS 1354015-99-8)
- 2-(Difluoromethyl)-4-hydroxy-6-(trifluoromethoxy)pyridine-3-acetonitrile (CAS 1804839-36-8)
- 2-(Difluoromethyl)-5-hydroxy-3-nitropyridine-6-methanol (CAS 1805206-20-5)
- 2-Methoxy-N-((2-(methylthio)pyrimidin-5-yl)methyl)ethan-1-amine (CAS 1279208-79-5)
- N-{1-[3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl]cyclohexyl}-1H-pyrazole-3-carboxamide (CAS 1396674-64-8)
- (2-Chloro-4-((2-methoxyethyl)carbamoyl)phenyl)boronic acid (CAS 2096336-58-0)
- 2-(4-Bromo-phenyl)-4-chloro-7-fluoro-quinazoline (CAS 885277-86-1)
- Neuropeptide W-23 (human) (CAS 383415-79-0)
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