1-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)pyrrolidine CAS 656257-46-4
| CAS No. | 656257-46-4 |
| Molecular Formula | C18H28BNO3 |
| Molecular Weight | 317.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)pyrrolidine (CAS 656257-46-4), a certified reference material (molecular formula C18H28BNO3, MW 317.23 g/mol) for analytical method development and quality control.
The molecular framework of 1-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)pyrrolidine (C18H28BNO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H28BNO3 |
| Molecular Weight | 317.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
Related Tetramethyl Standards
- 1-Methyl-4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)-1,4-diazepane (CAS 1015242-02-0)
- 4-(1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)morpholine (CAS 1206594-12-8)
- 1-Ethyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine (CAS 1447764-67-1)
- 4-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenethyl)morpholine (CAS 364794-82-1)
- 4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenethyl)morpholine (CAS 364794-81-0)
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- 3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl-thiazol-2-yl-methanol (CAS 2096997-09-8)
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trimethylsilyl)furo[3,2-b]pyridine (CAS 1188926-86-4)
Recommended Standards
- 1-(2,4-Dichloro-5-isopropoxyphenyl)-2-(methylthio)-1H-imidazole (CAS 338967-17-2)
- 2-(Cyclohexylmethoxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1346708-02-8)
- 1-(3-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine (CAS 2096340-00-8)
- N,N-Diethyl-2-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (CAS 1256359-90-6)
- 4-Cyano-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl 2,6-difluorobenzoate (CAS 956825-59-5)
- 3-(Furan-2-yl)pyrazine-2-carboxylic acid (CAS 1822827-80-4)
- 4-Benzyl-1-phenylisoquinolin-3(2H)-one (CAS 50845-51-7)
- 41891-54-7 Ethyl 4-(diethoxyphosphoryl)-3-methylbut-2-enoate Triethyl 3-Methyl-4-phosphonocrotonate;Triethyl (2E)-3-Methyl-4-phosphonocrotonate BCP21091 (CAS 41891-54-7)
- (9H-fluoren-9-yl)methyl azetidin-3-yl(methyl)carbamate (CAS 2163624-97-1)
- 4-[4-(2,5-Dimethyl-1H-pyrrol-1-yl)phenyl]-2-(pyridin-4-yl)pyrimidine (CAS 865658-64-6)
- 2-Amino-4-(4-iodo-1h-pyrazol-1-yl)-2-methylbutanamide (CAS 1341404-87-2)
- 1-(3-Cyclopropyl-1-methyl-1h-1,2,4-triazol-5-yl)-2-methylpropan-1-amine (CAS 1342132-53-9)
- 1-tert-Butyl 2-methyl (2R)-2-methylazetidine-1,2-dicarboxylate (CAS 1384745-52-1)
- Human glucagon CRS (CAS 9007-92-5)
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