2,4-Dichloro-6,8-dimethoxyquinoline CAS 65628-72-0
| CAS No. | 65628-72-0 |
| Molecular Formula | C11H9Cl2NO2 |
| Molecular Weight | 258.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2,4-Dichloro-6,8-dimethoxyquinoline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 258.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2,4-Dichloro-6,8-dimethoxyquinoline (CAS 65628-72-0), a certified reference material (molecular formula C11H9Cl2NO2, MW 258.10 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9Cl2NO2 |
| Molecular Weight | 258.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dichloro Standards
- Methyl 2-(5,6-dichloro-1H-indol-3-yl)acetate (CAS 113537-13-6)
- 2,4-Dichloro-5,7-dimethoxyquinoline (CAS 161648-76-6)
- 2,3-Dichloro-6,7-dimethoxyquinoline (CAS 1710846-06-2)
- 1-(3,5-Dichloro-4-methylphenyl)pyrrolidine-2,5-dione (CAS 27746-64-1)
- 1,3-Dichloro-6,7-dimethoxyisoquinoline (CAS 24623-42-5)
- 2-(5,6-Dichloro-1H-indol-3-yl)propanoic acid (CAS 338744-31-3)
- 2-(5,7-Dichloro-2-methyl-1H-indol-3-yl)acetic acid (CAS 25177-67-7)
- 2,4-Dichloro-5,8-dimethoxyquinoline (CAS 63070-62-2)
Recommended Standards
- 2,4-Dichloro-7,8-dimethoxyquinoline (CAS 202824-49-5)
- 2,6-Dichloro-3-fluoro-4-((methylsulfonyl)methyl)pyridine (CAS 2756590-39-1)
- 3-(3,4-Dichlorophenyl)-5-ethoxy-1H-1,2,4-triazole (CAS 62036-10-6)
- 2-(4-Chlorophenyl)quinolin-3-amine (CAS 5443-80-1)
- 5-Methylbenzo[4,5]thieno[3,2-b]quinolin-11(5H)-one (CAS 73394-24-8)
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- 7420-89-5 7E3L9OLC36 Disodium 1,5-dihydroxypentane-1,5-disulphonate 1,5-Pentanedisulfonic acid, 1,5-dihydroxy-, sodium salt (1:2) 1,5-Pentanedisulfonic acid, 1,5-dihydroxy-, disodium salt Sodium glutaraldehyde bisulfite EINECS 231-043-5 Glutaraldehyde bis(sodium bisulfite) Glutaraldehyde bisulfite Glutaraldehyde-sodium bisulfite NSC 34255 UNII-7E3L9OLC36 EINECS 249-339-8 (CAS 7420-89-5)
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- Nicorandil impurity 68 (CAS CATO-C4X-190768)
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