7-Hydroxy-4-methoxy-2H-chromen-2-one CAS 65692-17-3
| CAS No. | 65692-17-3 |
| Molecular Formula | C10H8O4 |
| Molecular Weight | 192.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-Hydroxy-4-methoxy-2H-chromen-2-one (CAS 65692-17-3), molecular formula C10H8O4 and molecular weight 192.17 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, 7-Hydroxy-4-methoxy-2H-chromen-2-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 192.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Hydroxy-4-methoxy-2H-chromen-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8O4 |
| Molecular Weight | 192.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
Related Hydroxy Standards
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- Methyl 6-hydroxy-1H-indazole-3-carboxylate (CAS 1082040-54-7)
- 3-Hydroxy-4-methoxy-2H-chromen-2-one (CAS 112212-18-7)
- 2-Hydroxy-4-oxo-4-phenylbut-2-enoic acid (CAS 113416-61-8)
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- 5-Hydroxy-4-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid (CAS 1190314-20-5)
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Recommended Standards
- 7-Amino-3-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 89977-62-8)
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- 7-Amino-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 2627-59-0)
- 7-Methoxy-1-benzofuran-4-carboxylic acid (CAS 33401-32-0)
- Lurasidone Impurity 6 (CAS 1365987-23-0)
- 5-(Furan-2-amido)-3-methylthiophene-2-carboxylic acid (CAS 923826-21-5)
- 4-(2-Hydrazinylthiazol-4-yl)benzene-1,2-diol (CAS 23251-16-3)
- Ethyl 2-(1-benzyl-3,3-difluoropiperidin-4-ylidene)acetate (CAS 1373510-82-7)
- 4,4'-(Quinoxaline-2,3-diyl)dianiline (CAS 2810-93-7)
- Acebutolol EP Impurity I (CAS 441019-91-6)
- 3-(3-Methyl-1-phenyl-1H-1,2,4-triazol-5-yl)-propanoic acid (CAS 1142209-42-4)
- 1,2,5-Thiadiazole-3,4-diamine 1,1-dioxide (CAS 55904-35-3)
- methyl 2-oxo-3-azabicyclo[3.1.1]heptane-1-carboxylate (CAS 1628783-91-4)
- C-telopeptide (CAS 162929-64-8)
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