4-Bromo-2,3,5-trifluoro-6-hydrazinylpyridine CAS 65717-66-0
| CAS No. | 65717-66-0 |
| Molecular Formula | C5H3BrF3N3 |
| Molecular Weight | 242.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Bromo-2,3,5-trifluoro-6-hydrazinylpyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-Bromo-2,3,5-trifluoro-6-hydrazinylpyridine (CAS 65717-66-0) is a high-purity analytical reference standard with the molecular formula C5H3BrF3N3 and a molecular weight of 242.00 g/mol.
The molecular framework of 4-Bromo-2,3,5-trifluoro-6-hydrazinylpyridine (C5H3BrF3N3) is characterized by a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H3BrF3N3 |
| Molecular Weight | 242.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
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- 4-Bromo-2-(trifluoromethyl)pyrimidin-5-amine (CAS 2271372-92-8)
Recommended Standards
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