1H-Indol-5-amine xhydrochloride CAS 65795-92-8
| CAS No. | 65795-92-8 |
| Molecular Formula | C8H8N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1H-Indol-5-amine xhydrochloride (CAS 65795-92-8), molecular formula C8H8N2HCl and molecular weight 168.62 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1H-Indol-5-amine xhydrochloride (C8H8N2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H8N2 HCl |
| Molecular Weight | 168.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related H Standards
- 1-(1h-Indol-3-yl)-2-methylpropan-2-ol (CAS 10006-90-3)
- 2-(1H-Indol-3-yl)propan-1-ol (CAS 10006-92-5)
- 1H-INdol-5-amine, 4-ethyl- (CAS 1003858-71-6)
- 2-(Indol-3-yl)ethylisocyanide (CAS 100571-64-0)
- 1-(1H-Indol-7-yl)ethanamine (CAS 1007877-68-0)
- 1-(1H-indol-4-yl)ethanamine (CAS 1007877-69-1)
- 1-((1H-indol-3-yl)methyl)piperidine-4-carboxylic acid (CAS 100957-76-4)
- 2-(1H-Indol-3-yl)-2-(pyrrolidin-1-yl)acetic acid (CAS 1010916-05-8)
Recommended Standards
- 2,3-Diaminofluorene (CAS 49670-63-5)
- 2,3-Dimethylpyrazine 1-oxide (CAS 65464-21-3)
- 2-Piperidin-3-yl-1,3-benzoxazole (CAS 754126-86-8)
- 2-(4-(4-Ethoxyphenyl)-2-morpholinothiazol-5-yl)acetic acid (CAS 1443290-05-8)
- (R)-3-Amino-4-(3-fluorophenyl)butanoic acid hydrochloride (CAS 331763-65-6)
- N-(2-chloro-4-nitrophenyl)-2-((3-cyano-6-phenyl-4-(p-tolyl)pyridin-2-yl)thio)acetamide (CAS 332127-70-5)
- 9-Ethylfluorene (CAS 2294-82-8)
- 2-(2,5-Dichlorothiophene-3-carboxamido)-6-isopropyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride (CAS 1185134-54-6)
- 3-Phenyl-1,2-dihydroquinoxaline-2-carboxylic acid (CAS 1218060-77-5)
- Neuroendocrine Regulatory Peptide-1 (human) (H-6622.1000) (CAS 954420-50-9)
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