3-Fluoro-5-iodoaniline CAS 660-49-1
| CAS No. | 660-49-1 |
| Molecular Formula | C6H5FIN |
| Molecular Weight | 237.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Fluoro-5-iodoaniline (C6H5FIN) is characterized by a nitrile group, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
3-Fluoro-5-iodoaniline (CAS 660-49-1), molecular formula C6H5FIN and molecular weight 237.01 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Fluoro-5-iodoaniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H5FIN |
| Molecular Weight | 237.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 2-Fluoro-5-iodo-4-methylpyridine (CAS 1184913-75-4)
- 3-Fluoro-5-iodo-2-methylpyridine (CAS 1211589-66-0)
- 2-Fluoro-3-iodo-4-methylpyridine (CAS 1214323-08-6)
- 2-Fluoro-3-iodoaniline (CAS 1261500-65-5)
- 2-Fluoro-4-iodo-3-picoline (CAS 153034-80-1)
- 2-Fluoro-4-iodo-5-methylpyridine (CAS 153034-94-7)
- 3-Fluoro-2-iodo-4-methylpyridine (CAS 153035-05-3)
- 2-Fluoro-4-iodo-6-methylpyridine (CAS 884494-45-5)
Recommended Standards
- 3-Fluoro-4-iodoaniline (CAS 656-66-6)
- 4-Fluoro-2-iodoaniline (CAS 61272-76-2)
- 3-Fluoro-2-iodoaniline (CAS 706752-99-0)
- 4-Fluoro-3-iodoaniline (CAS 647025-62-5)
- Bruceantin (CAS 41451-75-6)
- Benzoic acid, 4-bromo-2-ethyl- (9CI) (CAS 644984-78-1)
- 2-(2-Hydroxyethoxy)benzoic acid (CAS 55211-84-2)
- 7-Amino-[1,2,4]triazolo[4,3-a]pyrimidine-6-carbonitrile (CAS 28524-59-6)
- Dapsone-d4 (CAS 1346602-12-7)
- 5-Chloro-N-(3-cyanophenyl)furan-2-carboxamide (CAS 923184-50-3)
- Methyl 2-ethylÂthiopropionate (CAS 18673-13-7)
- 3-((tert-Butoxycarbonyl)amino)-2-fluorobenzoic acid (CAS 1517265-62-1)
- 2-Amino-6-chloro-4-(pyridin-3-yl)-4H-benzo[h]chromene-3-carbonitrile (CAS 414907-28-1)
- Peptide YY (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 81858-94-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com