2-(3-Chlorophenyl)succinic acid CAS 66041-28-9
| CAS No. | 66041-28-9 |
| Molecular Formula | C10H9ClO4 |
| Molecular Weight | 228.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(3-Chlorophenyl)succinic acid (CAS 66041-28-9), molecular formula C10H9ClO4 and molecular weight 228.63 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(3-Chlorophenyl)succinic acid (C10H9ClO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 2-(3-Chlorophenyl)succinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H9ClO4 |
| Molecular Weight | 228.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
Related Chlorophenyl Standards
- 2-(2-Chlorophenyl)succinic Acid (CAS 6954-40-1)
- 2-(4-Chlorophenyl)succinic acid (CAS 58755-91-2)
- 2-{[(3-chlorophenyl)carbamoyl]amino}acetic acid (CAS 501074-67-5)
- 2-(2-Chlorophenyl)-1H-imidazole-4,5-dicarbonitrile (CAS 41021-16-3)
- 2-(4-Chlorophenyl)-5-hydroxypentanoic acid (CAS 1017788-85-0)
- 2-(3-Chlorophenyl)benzofuran (CAS 65246-45-9)
- 2-(4-Chlorophenyl)benzofuran (CAS 39195-66-9)
- 3-(4-Chlorophenyl)benzofuran (CAS 57329-30-3)
Recommended Standards
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Why CATO?
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