(1R,4S)-1,2,3,4-tetrahydronaphthalene-1,4-diol CAS 661461-05-8

Purity 97%+In StockPharmaceutical Standards
CAS No.661461-05-8
Molecular FormulaC10H12O2
Molecular Weight164.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(1R,4S)-1,2,3,4-tetrahydronaphthalene-1,4-diol CAS 661461-05-8 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO supplies (1R,4S)-1,2,3,4-tetrahydronaphthalene-1,4-diol (CAS 661461-05-8), a certified reference material (molecular formula C10H12O2, MW 164.20 g/mol) for analytical method development and quality control.

The molecular framework of (1R,4S)-1,2,3,4-tetrahydronaphthalene-1,4-diol (C10H12O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H12O2
Molecular Weight164.20 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985

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