6-(Methylsulfonyl)nicotinonitrile CAS 66154-68-5
| CAS No. | 66154-68-5 |
| Molecular Formula | C7H6N2O2S |
| Molecular Weight | 182.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 182.20 g/mol gives 6-(Methylsulfonyl)nicotinonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 6-(Methylsulfonyl)nicotinonitrile (CAS 66154-68-5), a certified reference material (molecular formula C7H6N2O2S, MW 182.20 g/mol) for analytical method development and quality control.
6-(Methylsulfonyl)nicotinonitrile (C7H6N2O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-(Methylsulfonyl)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6N2O2S |
| Molecular Weight | 182.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methylsulfonyl Standards
- 5-(Methylsulfonyl)nicotinonitrile (CAS 1780797-86-5)
- 2-(Methylsulfonyl)isonicotinonitrile (CAS 66154-69-6)
- 2-(Methylsulfonyl)nicotinonitrile (CAS 66154-66-3)
- 5-(Methylsulfonyl)picolinonitrile (CAS 848141-13-9)
- 6-(Methylsulfonyl)picolinonitrile (CAS 342616-84-6)
- 2-Methyl-2-(methylsulfonyl)propanethioamide (CAS 2137602-48-1)
- 1-(Methylsulfonyl)piperidin-4-amine-d3 (CAS 2754355-03-6)
- 2-(Methylsulfonyl)benzonitrile (CAS 89942-56-3)
Recommended Standards
- 5-Methoxythiazolo[5,4-d]pyrimidin-2-amine (CAS 920313-63-9)
- 5-Hydroxy-6-methyl-7H-thiazolo[3,2-a]pyrimidin-7-one (CAS 883017-26-3)
- 6,7-Dihydro-[1,4]oxathiino[2,3-c]pyridazine-3-carbaldehyde (CAS 943026-20-8)
- 5-Fluoro-2-(1-piperazinyl)pyrimidine (CAS 87789-49-9)
- 8-Methyl-4-(4-methylbenzoyl)-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1009242-00-5)
- N-Methyl-1-(5-methyl-1H-benzimidazol-2-yl)methanamine dihydrochloride (CAS 1158445-87-4)
- N-(4-chlorophenyl)-4-((4-chlorophenyl)thio)-2-phenylpyrimidine-5-carboxamide (CAS 477854-76-5)
- Methyl 4-(aminomethyl)-2-methoxybenzoate hydrochloride (CAS 1391358-23-8)
- (2,4-Dimethylphenyl)(isoquinolin-4-yl)methanone (CAS 1187171-84-1)
- 5-Ethoxy-1-(p-tolyl)-1H-1,2,3-triazole (CAS 103861-17-2)
- Methyl 3-(3-Hydroxyphenyl)-4-methylpentanoate (CAS 1142224-26-7)
- 4-(azetidin-1-yl)-6-chloro-2-cyclopropylpyrimidine (CAS 617718-49-7)
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](cyano)methyl}phenyl 4-chlorobenzene-1-sulfonate (CAS 400083-94-5)
- Insulin Degludec Impurity 16 (CAS CATO-C4X-215716)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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