4-Chloro-6-hydroxy-2-methyl-2H-pyran-3(6H)-one CAS 66187-15-3
| CAS No. | 66187-15-3 |
| Molecular Formula | C6H7ClO3 |
| Molecular Weight | 162.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-Chloro-6-hydroxy-2-methyl-2H-pyran-3(6H)-one (CAS 66187-15-3), a certified reference material (molecular formula C6H7ClO3, MW 162.57 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, 4-Chloro-6-hydroxy-2-methyl-2H-pyran-3(6H)-one is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 162.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H7ClO3 |
| Molecular Weight | 162.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 4-Chloro-5,6-dihydro-2H-pyran-3-carboxylic acid (CAS 1541667-98-4)
- O-((4-Chloro-3-methylisoxazol-5-yl)methyl)hydroxylamine (CAS 80728-24-1)
- 2-Chloro-3,4-difluoro-1-methylbenzene (CAS 1026525-97-2)
- 3-Chloro-2,6-difluorotoluene (CAS 1208075-98-2)
- 5-Chloro-1,3-difluoro-2-methylbenzene (CAS 1208076-23-6)
- 3-CHloro-2,4-difluorotoluene (CAS 1208078-10-7)
- 1-Chloro-3,5-difluoro-2-methylbenzene (CAS 1261488-03-2)
- 1-Chloro-2,3-difluoro-5-methylbenzene (CAS 1261685-47-5)
Recommended Standards
- 3-Acetyl-3-chlorodihydrofuranone (CAS 2986-00-7)
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- 5-Chloroisophthalonitrile (CAS 109292-88-8)
- 1-(3-Nitrophenyl)-1H-imidazole-4-carboxylic acid (CAS 934631-86-4)
- [1,1'-Biphenyl]-4,4'-diylbis(phosphonic acid) (CAS 13817-79-3)
- 4-Bromo-2-cyclopropylmethoxy-1-nitro-benzene (CAS 1369839-40-6)
- Ethyl 8-amino-4-oxo-4h-chromene-2-carboxylate (CAS 103195-35-3)
- 1-[(3-chlorophenyl)methyl]-1h-pyrazole-4-carboxylic acid (CAS 1006494-84-3)
- N-(3-methylbutan-2-yl)tetrahydro-2H-thiopyran-4-amine (CAS 1153144-38-7)
- (2E)-1-(2-Methylphenyl)-3-[4-(propan-2-yl)phenyl]prop-2-en-1-one (CAS 1623003-45-1)
- Imazethapyrammonium (CAS 101917-66-2)
- 5-((4-Fluorobenzyl)oxy)-N-(4-fluorophenethyl)-4-oxo-4H-pyran-2-carboxamide (CAS 1021093-91-3)
- Semaglutide impurity 48 (CAS CATO-C4X-222648)
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