2-Bromo-4-chloro-1-(chloromethyl)benzene CAS 66192-23-2
| CAS No. | 66192-23-2 |
| Molecular Formula | C7H5BrCl2 |
| Molecular Weight | 239.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Bromo-4-chloro-1-(chloromethyl)benzene (C7H5BrCl2) is characterized by chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-Bromo-4-chloro-1-(chloromethyl)benzene (CAS 66192-23-2) is a high-purity analytical reference standard with the molecular formula C7H5BrCl2 and a molecular weight of 239.92 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Bromo-4-chloro-1-(chloromethyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5BrCl2 |
| Molecular Weight | 239.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl/Br-containing |
Related Bromo Standards
- 1-Bromo-2,5-dichloro-3-methylbenzene (CAS 1000571-63-0)
- 1-Bromo-3-chloro-5-(chloromethyl)benzene (CAS 1060812-67-0)
- 1-Bromo-3,5-dichloro-2-methylbenzene (CAS 115615-19-5)
- 1-Bromo-3-chloro-2-(chloromethyl)benzene (CAS 1242284-61-2)
- 1-Bromo-4-chloro-2-(chloromethyl)benzene (CAS 1261678-76-5)
- 1-Bromo-2-chloro-3-(chloromethyl)benzene (CAS 1261790-43-5)
- 1-Bromo-2,4-dichloro-3-methylbenzene (CAS 127049-87-0)
- 6-Bromo-2,3-dichlorotoluene (CAS 1805023-65-7)
Recommended Standards
- 2-Bromo-1-chloro-4-(chloromethyl)benzene (CAS 880348-46-9)
- 3-Bromo-4,5-dichlorotoluene (CAS 960305-14-0)
- 2-Bromo-1,5-dichloro-3-methylbenzene (CAS 876493-68-4)
- 4-Bromo-2,6-dichlorotoluene (CAS 204930-37-0)
- (1-Methoxycyclopropoxy)trimethylsilane (CAS 84098-43-1)
- C-[3-(4-Chloro-phenyl)-1H-pyrazol-4-yl]-methylamine (CAS 1020052-19-0)
- 7-Fluoro-2-methyl-5-oxo-N-(3-(trifluoromethyl)phenyl)-5H-chromeno[2,3-b]pyridine-3-carboxamide (CAS 338778-21-5)
- 1-[(4-Bromo-2-fluorophenyl)methyl]-4-nitro-1h-pyrazole (CAS 1240568-53-9)
- 1-(4-Methoxy-3,5-dimethylphenyl)propan-1-ol (CAS 1314932-05-2)
- 5-isopropyl-1H-pyrazol-3-amine hydrochloride (CAS 1347814-85-0)
- 5-Amino-1-(3-(trifluoromethoxy)phenyl)-1H-pyrazole-4-carbonitrile (CAS 650628-48-1)
- 3,4-Dihydronaphthalene-2-sulfonyl chloride (CAS 17070-56-3)
- 4-(4-Bromophenyl)morpholine Hydrochloride (CAS 1186663-63-7)
- Semaglutide Impurity 180 (CAS CATO-C4X-2226180)
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