6,7-Dimethoxy-2-methylquinazoline-4(1H)-thione CAS 66299-70-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6,7-Dimethoxy-2-methylquinazoline-4(1H)-thione.

CATO supplies 6,7-Dimethoxy-2-methylquinazoline-4(1H)-thione (CAS 66299-70-5), a certified reference material (molecular formula C11H12N2O2S, MW 236.29 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 6,7-Dimethoxy-2-methylquinazoline-4(1H)-thione is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6,7-Dimethoxy-2-methylquinazoline-4(1H)-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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