Cefotiam Dihydrochloride CAS 66309-69-1
| CAS No. | 66309-69-1 |
| Molecular Formula | C18H23N9O4S3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Cefotiam Dihydrochloride (CAS 66309-69-1), a certified reference material (molecular formula C18H23N9O4S3HCl, MW 562.08 g/mol) for analytical method development and quality control.
The molecular framework of Cefotiam Dihydrochloride (C18H23N9O4S3HCl) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H23N9O4S3 2*HCl |
| Molecular Weight | 562.08 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 9 |
| Sulfur Atoms | 3 |
Related Cefotiam Standards
- delta(3)-Cefotiam (CAS 142182-63-6)
- Cefotiam Impurity 2 (CAS 1566599-01-6)
- Cefotiam Impurity 6 (CAS 1628441-02-0)
- Cefotiam Impurity 4 (CAS 1628441-07-5)
- Cefotiam Impurity 16 (CAS 1628441-07-5(Free Base))
- Cefotiam Impurity 28 (CAS 18997-69-8)
- Cefotiam Impurity 8 (CAS 58233-18-4)
- Cefotiam Impurity 7 (CAS 61607-66-7)
Recommended Standards
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- 1-(4-Butylphenyl)heptan-1-one (CAS 1352222-62-8)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com