5-Bromo-N-(3-chloro-4-fluorophenyl)-2-hydroxybenzamide CAS 663152-26-9

Purity 97%+In StockPharmaceutical Standards
CAS No.663152-26-9
Molecular FormulaC13H8BrClFNO2
Molecular Weight344.56 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Bromo-N-(3-chloro-4-fluorophenyl)-2-hydroxybenzamide CAS 663152-26-9 chemical structure

Description

The occurrence of 5-Bromo-N-(3-chloro-4-fluorophenyl)-2-hydroxybenzamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-Bromo-N-(3-chloro-4-fluorophenyl)-2-hydroxybenzamide (CAS 663152-26-9), molecular formula C13H8BrClFNO2 and molecular weight 344.56 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 5-Bromo-N-(3-chloro-4-fluorophenyl)-2-hydroxybenzamide (C13H8BrClFNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 344.56 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Bromo-N-(3-chloro-4-fluorophenyl)-2-hydroxybenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H8BrClFNO2
Molecular Weight344.56 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentF/Cl/Br-containing
Nitrogen Atoms1

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