2-Ethyl-7-fluoro-3-methyl-4-nitro-1H-indole CAS 663177-51-3

Purity 97%+In StockPharmaceutical Standards
CAS No.663177-51-3
Molecular FormulaC11H11FN2O2
Molecular Weight222.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Ethyl-7-fluoro-3-methyl-4-nitro-1H-indole CAS 663177-51-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Ethyl-7-fluoro-3-methyl-4-nitro-1H-indole.

2-Ethyl-7-fluoro-3-methyl-4-nitro-1H-indole (CAS 663177-51-3), molecular formula C11H11FN2O2 and molecular weight 222.22 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-Ethyl-7-fluoro-3-methyl-4-nitro-1H-indole (C11H11FN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 2-Ethyl-7-fluoro-3-methyl-4-nitro-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H11FN2O2
Molecular Weight222.22 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentF-containing
Nitrogen Atoms2

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Why CATO?