4-(3,4-Dimethylphenyl)-5-methyl-4H-1,2,4-triazole-3-thiol CAS 663181-78-0
| CAS No. | 663181-78-0 |
| Molecular Formula | C11H13N3S |
| Molecular Weight | 219.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(3,4-Dimethylphenyl)-5-methyl-4H-1,2,4-triazole-3-thiol (CAS 663181-78-0), molecular formula C11H13N3S and molecular weight 219.31 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(3,4-Dimethylphenyl)-5-methyl-4H-1,2,4-triazole-3-thiol (C11H13N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 4-(3,4-Dimethylphenyl)-5-methyl-4H-1,2,4-triazole-3-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H13N3S |
| Molecular Weight | 219.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Dimethylphenyl Standards
- 4-(2,4-Dimethylphenyl)-2-hydrazinylthiazole (CAS 299168-61-9)
- 4-(2,5-Dimethylphenyl)-2-hydrazinylthiazole (CAS 886494-93-5)
- 4-(3,4-Dimethylphenyl)-2-hydrazinylthiazole (CAS 886495-65-4)
- 4-(3,5-Dimethylphenyl)-2-hydrazinylthiazole (CAS 886495-59-6)
- (2-(3,4-Dimethylphenyl)thiazol-4-yl)methanol (CAS 885280-35-3)
- (2-(3,5-Dimethylphenyl)thiazol-4-yl)methanol (CAS 885278-84-2)
- 1-(2,4-Dimethylphenyl)-3-thioxopyrrolidine-2,5-dione (CAS 88892-84-6)
- 1-(2,5-Dimethylphenyl)-5-thioxopyrrolidin-2-one (CAS 634151-19-2)
Recommended Standards
- 4-(2-Ethylphenyl)-5-methyl-4H-1,2,4-triazole-3-thiol (CAS 669755-34-4)
- 4-(4-(Dimethylamino)phenyl)thiazol-2-amine (CAS 874816-07-6)
- 4-(4-Ethylphenyl)-2-hydrazinylthiazole (CAS 61323-65-7)
- 4-(4-Ethylphenyl)-5-methyl-4H-1,2,4-triazol-3-yl hydrosulfide (CAS 663181-79-1)
- Methyl 2-(morpholinomethyl)piperidine-4-carboxylate (CAS 1398504-32-9)
- 4-(n,1,3-Trimethyl-1h-pyrazole-5-carboxamido)butanoic acid (CAS 1496463-90-1)
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- 6-Amino-2,2-dimethylchroman-4-one (CAS 186774-62-9)
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