Cefotaxime EP Impurity B CAS 66340-28-1
| CAS No. | 66340-28-1 |
| Molecular Formula | C14H15N5O6S2 |
| Molecular Weight | 413.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C14H15N5O6S2, Cefotaxime EP Impurity B contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 413.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Cefotaxime EP Impurity B (CAS 66340-28-1), a pharmacopoeial impurity reference standard (molecular formula C14H15N5O6S2, MW 413.43 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Cefotaxime EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H15N5O6S2 |
| Molecular Weight | 413.43 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Cefotaxime Standards
- Cefotaxime Impurity 21 (CAS CATO-C4X-120121)
- Cefotaxime Impurity 24 (CAS CATO-C4X-120124)
- Cefotaxime open ring lactone (CAS CATO-C4X-120141)
- Cefotaxime Impurity 76 (CAS CATO-C4X-120176)
- Cefotaxime Impurity 97 (CAS CATO-C4X-120197)
- Cefotaxime Impurity 50 (CAS CATO-C4X-120150)
- Cefotaxime Impurity 50 (CAS CATO-C4X-120157)
- Cefotaxime Impurity 95 (CAS CATO-C4X-120195)
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Why CATO?
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