Acyclovir Monophosphate CAS 66341-16-0
| CAS No. | 66341-16-0 |
| Molecular Formula | C8H12N5O6P |
| Molecular Weight | 305.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Acyclovir Monophosphate.
Acyclovir Monophosphate (CAS 66341-16-0), molecular formula C8H12N5O6P and molecular weight 305.18 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Acyclovir Monophosphate (C8H12N5O6P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.5, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 305.18 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Acyclovir Monophosphate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H12N5O6P |
| Molecular Weight | 305.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 5 |
Related Acyclovir Standards
- Acyclovir-d4 N,O-Diacetate (CAS 1189728-07-1)
- Acyclovir Impurity 31 (CAS CATO-C4X-101031)
- Acyclovir Impurity 15 (CAS CATO-C4X-101015)
- Acyclovir Impurity O (CAS 2190509-40-9)
- Acyclovir EP Impurity H (CAS 133186-23-9)
- Acyclovir-d4 (CAS 1185179-33-2)
- Acyclovir (CAS 59277-89-3)
- Acyclovir EP Impurity P (CAS 23169-33-7)
Recommended Standards
- 5-(3,5-Bis(trifluoromethyl)phenyl)furan-2-carbonitrile (CAS 2197056-54-3)
- Benzyl (2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethyl)carbamate (CAS 2377607-52-6)
- 4-Amino-1-((3aR,4R,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-2-oxidotetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl)pyrimidin-2(1H)-one (CAS 633-90-9)
- Ethyl 4-chloro-2-(chloromethyl)-5-methylthieno[2,3-d]pyrimidine-6-carboxylate (CAS 554439-97-3)
- 2-(3-Mercapto-5-(thiophen-2-yl)-4h-1,2,4-triazol-4-yl)-N-methylpropanamide (CAS 1290825-21-6)
- (4-Ethoxy-2,3-difluorophenyl)methanamine (CAS 1017779-64-4)
- [1-(2-Chloro-acetyl)-3-oxo-piperazin-2-yl]-acetic acid ethyl ester (CAS 1101199-66-9)
- N-(3-Chloro-4-fluorophenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775354-26-1)
- 2-(propylamino)ethanol (CAS 16369-21-4)
- Methyl 5-methylpyrazolo[1,5-a]pyridine-3-carboxylate (CAS 1167055-25-5)
- H-Gly-Gln-Gly-OH (CAS 2650-69-3)
- Fudosteine Impurity 8 (CAS CATO-C4X-14478)
- N-((1-Phenyl-1H-tetrazol-5-yl)methyl)-2-(m-tolyloxy)acetamide (CAS 920462-87-9)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
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