3-(4-Methoxybenzyl)phthalide 3-(p-Methoxybenzyl)phthalide 3-[(4-Methoxyphenyl)methyl]-1(3H)-isobenzofuranone 66374-23-0 CAS 66374-23-0
| CAS No. | 66374-23-0 |
| Molecular Formula | C16H14O3 |
| Molecular Weight | 254.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-(4-Methoxybenzyl)phthalide 3-(p-Methoxybenzyl)phthalide 3-[(4-Methoxyphenyl)methyl]-1(3H)-isobenzofuranone 66374-23-0 (CAS 66374-23-0), molecular formula C16H14O3 and molecular weight 254.28 g/mol, is a CATO reference standard with documented purity and traceability.
3-(4-Methoxybenzyl)phthalide 3-(p-Methoxybenzyl)phthalide 3-[(4-Methoxyphenyl)methyl]-1(3H)-isobenzofuranone 66374-23-0 (C16H14O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H14O3 |
| Molecular Weight | 254.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
Related Methoxybenzyl Standards
- 3-(1-(4-Methoxybenzyl)-1H-pyrrol-2-yl)-3-oxopropanenitrile (CAS 1403565-92-3)
- 6-(4-Methoxybenzyl)-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one (CAS 919093-57-5)
- 1-(4-Methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-3-amine (CAS 1968547-14-9)
- 5-((4-Methoxybenzyl)thio)-1,3,4-thiadiazol-2-amine (CAS 110076-50-1)
- 3-(4-Methoxybenzyl)-2-thioxo-1,3-thiazolidin-4-one (CAS 34396-47-9)
- 3-(4-Methoxybenzyl)indolin-2-one (CAS 170956-93-1)
- 1-(4-Methoxybenzyl)-1H-pyrrolo[2,3-b]pyridin-4-amine 1801335-41-0 (CAS 1801335-41-0)
- 1-(3-Methoxybenzyl)-1H-indazol-5-amine (CAS 930606-51-2)
Recommended Standards
- (2E)-3-[4-(benzyloxy)phenyl]prop-2-enoic acid 3-[4-(Benzyloxy)phenyl]acrylic acid 3-[4-(Benzyloxy)phenyl]prop-2-enoic acid 6272-45-3 (CAS 6272-45-3)
- 890099-33-9 3-(3-Methylbenzoyl)phenyl acetate DTXSID70641621 (CAS 890099-33-9)
- β-Carboline-3-carboxylic acid propyl ester (CAS 76808-18-9)
- 91147-07-8 Methyl 3-(9H-pyrido(3,4-b)indol-1-yl)propanoate DTXSID40238426 (CAS 91147-07-8)
- (S)-2-(3,4,5-TRIMETHOXYPHENYL)BUTYRIC ACID (CAS 195202-08-5)
- Spiromustine (CAS 56605-16-4)
- 4-Butoxybenzenesulfonamide (CAS 1138-58-5)
- 2-Boronobenzo[b]thiophene-6-carboxylic acid (CAS 946427-46-9)
- (3-Amino-6-bromobenzofuran-2-yl)methanol (CAS 1823913-31-0)
- 2-Amino-4-fluoro-2-methylbutanoic acid (CAS 208927-45-1)
- Ethyl azetidine-2-carboxylate (CAS 766483-76-5)
- (2-(Adamantan-1-yl)-2-oxoethyl)triphenylphosphonium bromide (CAS 17760-78-0)
- 4-Bromo-6-methoxyquinoline-3-carbonitrile (CAS 872714-52-8)
- Insulin Degludec Impurity 2 (CAS CATO-C4X-21572)
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